88376-97-0Relevant academic research and scientific papers
Synthetic Studies on Cembranolides. Stereoselective Synthesis of Epoxy Ester Intermediates
Marshall, James A.,Coghlan, Michael J.,Watanabe, Masataka
, p. 747 - 753 (1984)
A stereorational synthesis of the epimeric epoxy esters 17 and 21 from methacrolein is described.The route employs two key stereodirected steps.The first, copper-catalyzed addition of vinylmagnesium bromide to conjugated lactone 7, gives the trans product
