
Journal of Organic Chemistry p. 747 - 753 (1984)
Update date:2022-08-04
Topics:
Marshall, James A.
Coghlan, Michael J.
Watanabe, Masataka
A stereorational synthesis of the epimeric epoxy esters 17 and 21 from methacrolein is described.The route employs two key stereodirected steps.The first, copper-catalyzed addition of vinylmagnesium bromide to conjugated lactone 7, gives the trans product
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