884-74-2Relevant articles and documents
Cyclooctene epoxidation with H2O2 and single crystal X-ray determined crystal structures of new molybdenum and tungsten catalysts bearing the hydrophilic ligand hydroxymethyldiphenylphosphine oxide
Feng, Linsheng,Urnezius, Eugenijus,Luck, Rudy L.
, p. 1564 - 1571 (2008)
The dioxo molybdenum and tungsten complexes MoO2Cl2(OPPh2CH2OH)2 and WO2Cl2(OPPh2CH2OH)2 have been synthesized and characterized by FT-IR, 1
C-2 auxiliaries for stereoselective glycosylation based on common additive functional groups
Boltje, Thomas J.,De Kleijne, Frank F. J.,Moons, Sam J.,White, Paul B.
, p. 1165 - 1184 (2020/02/22)
The stereoselective introduction of the glycosidic bond is one of the main challenges in chemical oligosaccharide synthesis. Stereoselective glycosylation can be achieved using neighbouring group participation of a C-2 auxiliary or using additives, for example. Both methods aim to generate a defined reactive intermediate that reacts in a stereoselective manner with alcohol nucleophiles. This inspired us to develop new C-2 auxiliaries based on commonly used additive functionalities such as ethers, phosphine oxides and tertiary amides. Good 1,2-trans-selectivity was observed for the phosphine oxide and amide-based auxiliaries expanding the toolbox with new auxiliaries for stereoselective glycosylation reactions.
Reduction of Tertiary Phosphine Oxides by BH 3 Assisted by Neighboring Activating Groups
Sowa, Sylwia,Stankevi?, Marek,Flis, Anna,Pietrusiewicz, K. Micha?
, p. 2106 - 2118 (2018/02/28)
Tertiary sulfanylphosphine and aminoalkylphosphine oxides can be easily converted into the corresponding tertiary sulfanylphosphine- and aminoalkylphosphine-boranes, respectively, through the facile P=O bond reduction by borane complexes. The easy reduction of the strong P=O bond by BH 3, a mild reducing agent, has been achieved through an intramolecular P=O - B complexation directed by proximal SH or NH activating groups located at the α- or β-position to the P=O bond. A generalized reduction mechanism has been proposed.