88425-23-4Relevant academic research and scientific papers
Non-Kolbe electrolysis of
Adamek, J.,Michalak, M.,Pa?dzierniok-Holewa, A.,Wal?cka-Kurczyk, A.,Walczak, K.
, p. 2107 - 2114 (2022/02/07)
Here, we report a standardized method for the synthesis of N-protected (1-methoxyalkyl)amines by the electrochemical decarboxylative α-methoxylation of α-amino acid derivatives using the commercially available, easy-to-use, compact ElectraSyn 2.0 setup. T
Catalyst-free Mannich-type reaction of 1-(N-acylamino)alkyltriphenylphosphonium salts with silyl enolates
Pa?dzierniok-Holewa, Agnieszka,Wal?cka-Kurczyk, Alicja,Musio?, Szymon,Stecko, Sebastian
, p. 732 - 742 (2019/01/10)
A catalyst-free reaction of 1-(N-acylamino)alkyltriphenylphosphonium tetrafluoroborates with silyl enolates was developed to prepare β-amino carbonyl compounds. The reported method is a useful approach for the preparation of N-protected β-amino esters as
Diastereoselective preparation of novel tetrahydrooxazinones via heterocycloaddition of N-Boc, O-Me-acetals
Gizecki, Patricia,Ait Youcef, Ramzi,Poulard, Céline,Dhal, Robert,Dujardin, Gilles
, p. 9589 - 9592 (2007/10/03)
Under Lewis acid conditions, reaction of N-Boc, O-Me acetals with the (R)-(+)-O-vinyl-pantolactone does not lead to the expected dihydrooxazine, but to the corresponding tetrahydrooxazinone, as a result of the loss of the t-Bu group. A diastereoselective
Retro-Inverso Isomerization of Peptides: Side Reactions in the Synthesis of N,N'-Diacyl-1,1-diamino-2-phenylethane Derivatives
Chorev, Michael,MacDonald, Scott A.,Goodman, Murray
, p. 821 - 827 (2007/10/02)
In general, the synthesis of retro-inverso peptides requires the formation of diacylated gem-diaminoalkyl structures.One way to prepare these gem-diaminoalkyl residues involves the Curtius rearrangement of the N-acylated amino acid hydrazides to the corre
