884345-53-3

Upstream product

• 994-30-9 triethylsilyl chloride 
• 131375-65-0 7-(4-methoxyphenylmethoxy)-hept-2-en-1-ol 
• 131375-63-8 5-(4-methoxybenzyloxy)-1-pentanol 
• 865302-25-6 (2R,3R)-3-[4-(4-methoxyphenylmethoxy)butyl]oxirane-2-methanol 
• 884345-52-2 (2R,3R)-7-(4-methoxybenzyloxy)-2,3-epoxy-1-iodoheptane 

Downstream Products

• 884345-57-7 (S)-4-Benzyloxy-5-{(4R,6S)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-3,3-dimethyl-1-((2S,6R)-6-vinyl-tetrahydro-pyran-2-yl)-pentan-2-one 
• 884345-56-6 (E)-(2S,10R)-2-Benzyloxy-1-{(4R,6S)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-10-hydroxy-3,3-dimethyl-dodeca-5,11-dien-4-one 
• 884345-55-5 (E)-(2S,10R)-2-Benzyloxy-1-{(4R,6S)-6-[2-(tert-butyl-diphenyl-silanyloxy)-ethyl]-2,2-dimethyl-[1,3]dioxan-4-yl}-3,3-dimethyl-10-triethylsilanyloxy-dodeca-5,11-dien-4-one 

Relevant academic research and scientific papers

Some limitations of an approach to the assembly of bryostatins by ring-closing metathesis

Preliminary studies into the use of ring-closing metathesis (RCM) in a convergent approach for the total synthesis of bryostatins are described. An ester that would have provided an advanced intermediate for a synthesis of a 20-deoxybryostatin by a RCM wa

A preliminary evaluation of a metathesis approach to bryostatins

Preliminary investigations into the synthesis of bryostatins using ring-closing metathesis to form the C(16)-C(17) double bond led to a synthesis of the bryostatin analogue 51; precursors 26 and 52, which possess the geminal dimethyl group at C-18, did no