88522-38-7Relevant academic research and scientific papers
Synthesis and antimalarial activity of sulfonamide chalcone derivatives
Dominguez, Jose N.,Leon, Caritza,Rodrigues, Juan,De Dominguez, Neira Gamboa,Gut, Jiri,Rosenthal, Philip J.
, p. 307 - 311 (2005)
A series of sulfonamide chalcone derivatives were synthesized and investigated for their abilities to inhibit β-hematin formation in vitro and their activity against cultured Plasmodium falciparum parasites. Inhibition of β-hematin formation was minimal i
The discrete role of chlorine substitutions in the conformation and supra-molecular architecture of aryl-sulfonamides
Fernandes, William B.,Aragao, Angelo Q.,Martins, Felipe T.,Noda-Perez, Caridad,Lariucci, Carlito,Napolitano, Hamilton B.
body text, p. o226-o229 (2011/08/21)
Two aryl-sulfonamide derivatives, N-(4-acetyl-phen-yl)benzene-sulfonamide, C14H13NO3S, and N-(4-acetyl-phen-yl)-2,5-di- chloro-benzene-sulfonamide, C14H11Cl2NO 3S, differing by t
Synthesis of some novel cyanopyridines and isoxazoles bearing sulphonamide moiety and their antimicrobial activity
Patel, V. B.,Sorathiya, S. D.,Parikh, A. R.
, p. 822 - 825 (2007/10/03)
Substituted 2-propen-1-ones 2a-h, prepared by the reaction of p-(2,5-dichlorobenzenesulphonamido)acetophenone 1 with araldehydes, on condensation with malononitrile in the presence of ammonium accetate yield cyanopyridines 3a-h. Also 2a-h on reaction with hydroxylamine hydrochloride in the presence of sodium acetate in acetic acid afford isoxazoles 4a-h. The structures of 3a-h and 4a-h have been established on the basis of elemental analyses and spectral (IR, 1H NMR and mass) data. The products have been screened for their antimicrobial activity against various strains of bacteria and fungi.
2,5-Dichlorobenzenesulphonamide Derivatives and Their Biological Activities
El-Sharief, A. M. Sh.,Ammar, M. S.,Ammar, Y. A.,Zaki, M. E. A.
, p. 700 - 704 (2007/10/02)
2,5-Dichlorobenzenesulphonyl chloride (I) reacts with p-aminobenzoic acid to give IXc from which the corresponding esters (X), primary (XI) and secondary (XII) amides have been prepared.Reaction of I with hydrazine hydrate furnishes two hydrazides (XVIIIa
