885223-72-3

Basic information

• Product Name: 5-BROMO-6-METHYL-1H-INDAZOLE
• Synonyms: 1H-Indazole, 5-broMo-6-Methyl-;5-Bromo-6-methylindazole
• CAS NO: 885223-72-3
• Molecular Formula: C₈H₇BrN₂
• Molecular Weight: 211.07
• Product Categories: Building Blocks;Indazole
• Mol File: 885223-72-3.mol
• Article Data: 5

Chemical Properties

• Melting Point: 166-169°C
• Boiling Point: 344.6 °C at 760 mmHg
• Flash Point: 162.2 °C
• Appearance: /
• Density: 1.654 g/cm³
• Vapor Pressure: 0.00013mmHg at 25°C
• Refractive Index: 1.696
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 13.21±0.40(Predicted)
• CAS DataBase Reference: 5-BROMO-6-METHYL-1H-INDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-6-METHYL-1H-INDAZOLE(885223-72-3)
• EPA Substance Registry System: 5-BROMO-6-METHYL-1H-INDAZOLE(885223-72-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22-51
• WGK Germany: 3
• Hazardous Substances Data: 885223-72-3(Hazardous Substances Data)

Usage

General Description

5-Bromo-6-methyl-1H-indazole is a chemical compound with the molecular formula C9H8BrN3. It belongs to the class of indazole compounds, which are commonly used as building blocks for the synthesis of pharmaceuticals and agrochemicals. The specific structure of 5-Bromo-6-methyl-1H-indazole makes it suitable for various chemical reactions and transformations, and it has potential applications in medicinal chemistry and drug discovery. 5-Bromo-6-methyl-1H-indazole is known for its heterocyclic nature, which makes it a valuable component in the development of new drugs and research in the field of organic chemistry. Its properties and reactivity make it an important chemical for further study and potential applications in various industries.

InChI:InChI=1/C8H7BrN2/c1-5-2-8-6(3-7(5)9)4-10-11-8/h2-4H,1H3,(H,10,11)

Upstream product

• 95-78-3 2,5-Dimethylaniline 
• 2050-44-4 N-(2,5-dimethylphenyl)acetamide 
• 13711-31-4 N-(4-bromo-2,5-dimethyl-phenyl)acetamide 
• 1202527-94-3 1-acetyl-5-bromo-6-methyl-1H-indazole 
• 540-80-7 tert.-butylnitrite 
• 30273-40-6 4-bromo-2,5-dimethylaniline 

Downstream Products

• 1202528-03-7 5-bromo-1-(4-fluorophenyl)-6-methyl-1H-indazole 
• 1202527-96-5 Propyl-6-bromomethyl-1-methyl-1H-indazole-5-carboxylate 
• 1202527-98-7 1-methyl-6-phenoxymethyl-1H-indazole-5-carboxylic acid 
• 1202526-93-9 (E)-5-{1-[3-(methanesulfonamide)phenyl]propylidene}-1-methyl-5,11-dihydrobenzo[6,7]oxepino[4,3-f]indazole 
• 1202527-97-6 n-propyl-1-methyl-6-phenoxymethyl-1H-indazole-5-carboylate 
• 1312008-65-3 1,1-dimethylethyl 5-bromo-6-methyl-2H-indazole-2-carboxylate 
• 1305320-67-5 tert-butyl 5-bromo-6-methyl-1H-indazole-1-carboxylate 
• 259537-71-8 6-Methyl-1 H-indazole-5-carbonitrile 
• 1312009-23-6 ethyl 4-[5-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-6-methyl-1H-indazol-1-yl]butanoate 
• 1312009-24-7 ethyl 4-[5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-6-methyl-1H-indazol-1-yl]butanoate 
• 1312009-58-7 4-[5-(5-{3-cyano-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-6-methyl-1H-indazol-1-yl]butanoic acid 
• 1312009-59-8 4-[5-(5-{3-chloro-4-[(1-methylethyl)oxy]phenyl}-1,2,4-oxadiazol-3-yl)-6-methyl-1H-indazol-1-yl]butanoic acid 
• 1467061-53-5 5-(2-fluoro-4-methoxyphenyl)-6-methyl-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole 
• 1467061-54-6 ethyl 5-(2-fluoro-4-methoxyphenyl)-6-methyl-2-((2-(trimethylsilyl)ethoxy)methyl)-2H-indazole-3-carboxylate 

Relevant articles and documents

GPR40 RECEPTOR AGONIST, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT

The present invention relates to a novel compound having GPR40 receptor agonist activity that promotes insulin secretion and inhibits blood sugar rise after glucose loading, and is thereby useful for the treatment of diabetes and complications thereof, the preparation method thereof and pharmaceutical composition containing them as an active ingredient.

OXADIAZOLE SUBSTITUTED INDAZOLE DERIVATIVES FOR USE AS SPHINGOSINE 1-PHOSPHATE 1 (S1P1) RECEPTOR AGONISTS

Oxadiazole substituted indazole derivatives of formula (I) or pharmaceutical salts thereof having pharmacological activity, processes for their preparation, pharmaceutical compositions containing them and their uses in the treatment of various disorders mediated by S1P1 receptor are disclosed.

THIADIAZOLE COMPOUNDS AND METHODS OF USE

The invention relates to thiadiazole compounds useful for treating diseases mediated by protein kinase B (PKB). The invention also relates to the therapeutic use of such thiadiazole compounds and compositions thereof in treating disease states associated