885272-76-4

Basic information

• Product Name: (6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETONITRILE
• Synonyms: (6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETONITRILE
• CAS NO: 885272-76-4
• Molecular Formula: C16H13N3
• Molecular Weight: 247.29
• Mol File: 885272-76-4.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETONITRILE(885272-76-4)
• EPA Substance Registry System: (6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETONITRILE(885272-76-4)

Safety Data

• Hazardous Substances Data: 885272-76-4(Hazardous Substances Data)

Usage

General Description

"(6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETONITRILE" is a chemical compound with the molecular formula C15H11N3. It is a heterocyclic compound containing both imidazole and pyridine rings, which gives it unique properties and potential biological activities. It is also known as a nitrile, meaning it contains a cyano group (C≡N), which makes it a versatile building block in organic synthesis. (6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETONITRILE may have potential applications in drug discovery and development due to its structural features and potential biological activities. Further research and studies are needed to fully understand the properties and potential applications of "(6-METHYL-2-PHENYL-IMIDAZO[1,2-A]PYRIDIN-3-YL)-ACETONITRILE".

Upstream product

• 75-05-8 acetonitrile 
• 1019-89-2 6-methyl-2-phenylimidazo[1,2-a]pyridine 
• 1603-41-4 (5-methyl-pyridin-2-yl)amine 
• 70-11-1 α-bromoacetophenone 
• 590-17-0 cyanomethyl bromide 
• 13138-21-1 diazoacetonitrile 
• 151-50-8 potassium cyanide 
• 365213-38-3 N,N-dimethyl-1-(6-methyl-2-phenylimidazo[1,2-a]pyridin-3-yl)methanamine 

Relevant articles and documents

Synthesis of C3-Cyanomethylated Imidazo[1,2- a ]pyridines via Ultrasound-Promoted Three-Component Reaction under Catalyst- and Oxidant-Free Conditions

An efficient synthesis of C3-cyanomethylated imidazo[1,2-α]pyridines via ultrasound-promoted three-component reaction under catalyst-free, oxidant-free, and mild conditions has been developed. A series of C3-cyanomethylated imidazo[1,2-α]pyridines were rapidly prepared with satisfactory yields and good functional group compatibility. This strategy cloud also be applied to the synthesis of zolpidem and alpidem in short steps.

Synthesis method of naphtho[1', 2': 4, 5]imidazo[1, 2-a]pyridine-5, 6-diketone compound

The invention discloses a synthetic method of a naphtho[1', 2': 4, 5]imidazo[1, 2-a]pyridine-5, 6-diketone compound, which belongs to the technical field of organic chemistry. The synthesis method comprises the following steps: taking 2-aryl imidazo[1, 2-a] pyridine compound and diazonium acetonitrile as raw materials; synthesizing a 3-cyanomethylated imidazo[1, 2-a]pyridine compound 3 in the presence of a catalyst, reacting the compound 3 with an alcohol under the action of an acid to obtain an imidazo [1, 2-a] pyridine-3-acetate compound 4, and finally heating PPA to condense into a ring andsimutanously forms naphtho[1', 2': 4, 5]imidazo[1, 2-a]pyridine-5,6-dione 5. The whole process of the method is carried out in the air, the used catalysts are common catalysts, the method is low in cost and environmentally friendly, the raw materials are easy to obtain, and a new synthesis path is provided for the compounds.

Iron-Catalyzed Dehydrogenative sp3-sp2 Coupling via Direct Oxidative C-H Activation of Acetonitrile

An iron-catalyzed dehydrogenative sp3-sp2 coupling of acetonitrile and 2-arylimidazo[1,2-a]pyridine has been realized, which can serve as a novel approach toward heteroarylacetonitriles. The merit of this strategy is illustrated by the breadth of functional groups tolerated in the transformation and the fast access to pharmaceuticals (such as zolpidem) directly from the heteroarylacetonitriles.