885279-11-8

Basic information

• Product Name: 2-(2-METHOXY-PHENYL)-THIAZOLE-4-CARBALDEHYDE
• Synonyms: 2-(2-METHOXY-PHENYL)-THIAZOLE-4-CARBALDEHYDE;2-(2-Methoxyphenyl)-1,3-thiazole-4-carbaldehyde
• CAS NO: 885279-11-8
• Molecular Formula: C₁₁H₉NO₂S
• Molecular Weight: 219.26
• Mol File: 885279-11-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 398.2±48.0 °C(Predicted)
• Appearance: /
• Density: 1.266±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.28±0.10(Predicted)
• CAS DataBase Reference: 2-(2-METHOXY-PHENYL)-THIAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-METHOXY-PHENYL)-THIAZOLE-4-CARBALDEHYDE(885279-11-8)
• EPA Substance Registry System: 2-(2-METHOXY-PHENYL)-THIAZOLE-4-CARBALDEHYDE(885279-11-8)

Safety Data

• Hazardous Substances Data: 885279-11-8(Hazardous Substances Data)

Usage

General Description

2-(2-Methoxy-phenyl)-thiazole-4-carbaldehyde is a chemical compound that possesses the structural characteristics of methoxyphenyl and thiazole groups. Its molecular formula is C12H9NOS2, indicating that it is made up of carbon, hydrogen, nitrogen, oxygen, and sulfur atoms. 2-(2-METHOXY-PHENYL)-THIAZOLE-4-CARBALDEHYDE finds its importance in research and study within the field of organic chemistry and it may have potential applications in drug development or materials science due to its specific molecular structure, though further investigation and verification are needed. Its properties will be dependent on variables such as temperature, pressure, and interactions with other substances, and data about its toxicity, safety hazards, and environmental impact is limited.

Upstream product

• 115921-06-7 (R)-2-(2-hydroxyphenyl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid 
• 262419-96-5 (4R)-2-(2-hydroxyphenyl)-4,5-dihydrothiazole-4-carboxylic acid N-methoxy-N-methylamide 
• 828936-79-4 2'-(2-hydroxyphenyl)-2'-thiazole-4'-(N-methoxy-N-methyl)carboxamide 
• 1258769-07-1 C₁₃H₁₄N₂O₃S 
• 611-20-1 salicylonitrile 
• 115299-16-6 ethyl 2-(2-methoxyphenyl)thiazole-4-carboxylate 
• 187793-07-3 2-(2'-methoxyphenyl)-4-hydroxymethylthiazole 
• 5198-80-1 2-bromothiazole-4-carbaldehyde 
• 5720-06-9 2-Methoxyphenylboronic acid 

Relevant articles and documents

The photoredox-catalyzed hydrosulfamoylation of styrenes and its application in the novel synthesis of naratriptan

The hydrosulfamoylation of diverse aryl olefins provides facile access to alkylsulfonamides. Here we report a novel protocol utilizing radical-mediated addition and a thiol-assisted strategy to achieve the hydrosulfamoylation of diverse styrenes in modest to excellent yields under mild and economic reaction conditions. The methodology was found to provide an efficient and convenient approach for the synthesis of the anti-migraine drug naratriptan and it also can be used for the late-stage functionalization of natural products or medicines.

Synthesis and biological properties of thiazole-analogues of pyochelin, a siderophore of Pseudomonas aeruginosa

Pyochelin is a siderophore common to all strains of Pseudomonas aeruginosa utilized by this Gram-negative bacterium to acquire iron(III). FptA is the outer membrane transporter responsible of ferric-pyochelin uptake in P. aeruginosa. We describe in this Letter the synthesis and the biological properties ( 55Fe uptake, binding to FptA) of several thiazole analogues of pyochelin. Among them we report in this Letter the two first pyochelin analogues able to bind FptA without promoting any iron uptake in P. aeruginosa.