88547-24-4 Usage
General Description
AC-4,5-DEHYDRO-LEU-OH, also known as 4,5-dehydro-leucine, is a chemical compound with the molecular formula C6H11NO2. This organic compound is a derivative of leucine, an essential amino acid. It is known for its potential medical and pharmacological applications, including its role in the synthesis of peptide and protein molecules. AC-4,5-DEHYDRO-LEU-OH has also been studied for its potential antimicrobial properties and as a building block for the development of pharmaceutical drugs. Additionally, this compound has been investigated for its potential role in the treatment of neurological disorders and cancer. Overall, AC-4,5-DEHYDRO-LEU-OH is a versatile chemical with diverse potential applications in the fields of medicine, pharmacology, and biochemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 88547-24-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,5,4 and 7 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 88547-24:
(7*8)+(6*8)+(5*5)+(4*4)+(3*7)+(2*2)+(1*4)=174
174 % 10 = 4
So 88547-24-4 is a valid CAS Registry Number.
88547-24-4Relevant articles and documents
Total synthesis of cyclomarins A, C and D, marine cyclic peptides with interesting anti-tuberculosis and anti-malaria activities
Barbie, Philipp,Kazmaier, Uli
, p. 6036 - 6054 (2016/07/06)
Cyclomarins are cyclic heptapeptides containing four unusual amino acids. New synthetic protocols toward their synthesis have been developed, leading to the synthesis and biological evaluation of three natural occurring cyclomarins. Interestingly, cyclomarins address two completely different targets: Clp C1, a subunit of the caseinolytic protease of Mycobacterium tuberculosis (MTB), as well as PfAp3Ase of Plasmodium falciparum. Therefore, cyclomarins are interesting lead structures for the development of drugs against tuberculosis and malaria.
The total synthesis of eponemycin
Schmidt,Schmidt
, p. 300 - 304 (2007/10/02)
Eponemycin, an antibiotic with a highly potent and specific antitumor activity against B16 melanoma cells in vivo, has been synthesized. The framework of the western half of the molecule was built up from N-trityl- γ,δ-didehydroleucinal and the dilithium