88549-92-2

Upstream product

• 88549-90-0 N-((3R,4R,4aR,5R,6R,8R,8aS)-5,6-Dihydroxy-3-methyl-1-oxo-8-phenylselanylmethyl-octahydro-isochromen-4-yl)-C-p-tolyl-methanesulfonamide 
• 88549-91-1 N-((3R,4R,4aR,5R,6R,8aS)-5,6-Dihydroxy-3-methyl-8-methylene-1-oxo-octahydro-isochromen-4-yl)-C-p-tolyl-methanesulfonamide 
• 88549-85-3 (1aS,3R,3aR,6R,6aR,6bR)-6-((R)-1-Hydroxy-ethyl)-4-oxo-octahydro-1-oxa-5-aza-cyclopropa[e]indene-3-carboxylic acid methyl ester 
• 88549-83-1 (1R,3aR,4R,7aR)-3-Oxo-1-[(R)-1-(tetrahydro-pyran-2-yloxy)-ethyl]-2,3,3a,4,5,7a-hexahydro-1H-isoindole-4-carboxylic acid 
• 88549-81-9 Benzoic acid (Z)-(1R,2R)-2-((E)-3-ethoxycarbonyl-acryloylamino)-1-methyl-hexa-3,5-dienyl ester 
• 88549-87-5 (3aR,5R,5aS,8R,8aR,8bR)-5-Hydroxymethyl-2,2-dimethyl-8-[(R)-1-(tetrahydro-pyran-2-yloxy)-ethyl]-octahydro-[1,3]dioxolo[4,5-e]isoindol-6-one 
• 88549-84-2 (1R,2S,5R,6R,7S,8S)-7-Iodo-5-[(R)-1-(tetrahydro-pyran-2-yloxy)-ethyl]-9-oxa-4-aza-tricyclo[6.2.1.0^2,6]undecane-3,10-dione 
• 88549-86-4 (3aR,5R,5aR,8R,8aR,8bR)-2,2-Dimethyl-6-oxo-8-[(R)-1-(tetrahydro-pyran-2-yloxy)-ethyl]-octahydro-[1,3]dioxolo[4,5-e]isoindole-5-carboxylic acid methyl ester 
• 88549-88-6 (3aR,5R,5aR,8R,8aR,8bR)-2,2-Dimethyl-5-phenylselanylmethyl-8-[(R)-1-(tetrahydro-pyran-2-yloxy)-ethyl]-octahydro-[1,3]dioxolo[4,5-e]isoindol-6-one 
• 88549-89-7 (3R,3aR,4R,5R,7R,7aR)-4,5-Dihydroxy-3-((R)-1-hydroxy-ethyl)-7-phenylselanylmethyl-2-p-tolylmethanesulfonyl-octahydro-isoindol-1-one 
• 88549-94-4 (3aR,5R,5aR,8R,8aR,8bR)-8-((R)-1-Hydroxy-ethyl)-2,2-dimethyl-6-oxo-octahydro-[1,3]dioxolo[4,5-e]isoindole-5-carboxylic acid methyl ester 
• 88549-82-0 (1R,3aR,4R,7aR)-1-((R)-1-Benzoyloxy-ethyl)-3-oxo-2,3,3a,4,5,7a-hexahydro-1H-isoindole-4-carboxylic acid ethyl ester 
• 88549-82-0 (1R,3aR,4R,7aR)-1-((R)-1-Benzyloxy-ethyl)-3-oxo-2,3,3a,4,5,7a-hexahydro-1H-isoindole-4-carboxylic acid ethyl ester 

Downstream Products

• 88549-95-5 N-Cbz-actinobolin 

Relevant academic research and scientific papers

HIGHLY STEREOSELECTIVE SYNTHESIS OF ANTITUMOR ANTIBIOTICS, (+)-ACTINOBOLIN AND (-)-BACTOBOLIN, BY ASYMMETRIC CYCLIZATION

A common skeleton of (+)-actinobolin and (-)-bactobolin was efficiently formed by an intramolecular Diels-Alder reaction of a chiral Z diene with a substituent at the pentadienylic carbon, and the following transformation completed the first total synthes