88549-95-5

Upstream product

• 88549-87-5 (3aR,5R,5aS,8R,8aR,8bR)-5-Hydroxymethyl-2,2-dimethyl-8-[(R)-1-(tetrahydro-pyran-2-yloxy)-ethyl]-octahydro-[1,3]dioxolo[4,5-e]isoindol-6-one 
• 88549-84-2 (1R,2S,5R,6R,7S,8S)-7-Iodo-5-[(R)-1-(tetrahydro-pyran-2-yloxy)-ethyl]-9-oxa-4-aza-tricyclo[6.2.1.0^2,6]undecane-3,10-dione 
• 88549-86-4 (3aR,5R,5aR,8R,8aR,8bR)-2,2-Dimethyl-6-oxo-8-[(R)-1-(tetrahydro-pyran-2-yloxy)-ethyl]-octahydro-[1,3]dioxolo[4,5-e]isoindole-5-carboxylic acid methyl ester 
• 88549-92-2 C-p-Tolyl-N-((3R,4R,4aR,5R,6R)-5,6,8-trihydroxy-3-methyl-1-oxo-3,4,4a,5,6,7-hexahydro-1H-isochromen-4-yl)-methanesulfonamide 
• 88549-88-6 (3aR,5R,5aR,8R,8aR,8bR)-2,2-Dimethyl-5-phenylselanylmethyl-8-[(R)-1-(tetrahydro-pyran-2-yloxy)-ethyl]-octahydro-[1,3]dioxolo[4,5-e]isoindol-6-one 
• 88549-89-7 (3R,3aR,4R,5R,7R,7aR)-4,5-Dihydroxy-3-((R)-1-hydroxy-ethyl)-7-phenylselanylmethyl-2-p-tolylmethanesulfonyl-octahydro-isoindol-1-one 
• 88549-90-0 N-((3R,4R,4aR,5R,6R,8R,8aS)-5,6-Dihydroxy-3-methyl-1-oxo-8-phenylselanylmethyl-octahydro-isochromen-4-yl)-C-p-tolyl-methanesulfonamide 
• 126423-69-6 N-{(S)-1-[(3aS,4S,6S,7aS)-6-(tert-Butyl-dimethyl-silanyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxol-4-yl]-2-hydroxy-propyl}-C-p-tolyl-methanesulfonamide 
• 99457-40-6 2-oxabicyclo<3.3.1>non-6-ene-3,4-dione 
• 126423-69-6 N-{(1S,2S)-1-[(3aS,4S,6S,7aS)-6-(tert-Butyl-dimethyl-silanyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxol-4-yl]-2-hydroxy-propyl}-C-p-tolyl-methanesulfonamide 
• 126423-66-3 (R)-2-[(3aR,4R,6R,7aR)-6-(tert-Butyl-dimethyl-silanyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxol-4-yl]-N-methoxy-N-methyl-2-p-tolylmethanesulfonylamino-acetamide 
• 126423-70-9 Acetic acid (1S,2S)-2-[(3aS,4S,6S,7aS)-6-(tert-butyl-dimethyl-silanyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxol-4-yl]-1-methyl-2-p-tolylmethanesulfonylamino-ethyl ester 
• 126423-65-2 (S)-2-((3aS,4S,6S,7aS)-6-Hydroxy-2,2-dimethyl-hexahydro-benzo[1,3]dioxol-4-yl)-N-methoxy-N-methyl-2-p-tolylmethanesulfonylamino-acetamide 
• 126423-72-1 Acetic acid (1S,2S)-2-((3aS,4S,7aS)-2,2-dimethyl-6-oxo-hexahydro-benzo[1,3]dioxol-4-yl)-1-methyl-2-p-tolylmethanesulfonylamino-ethyl ester 

Relevant academic research and scientific papers

Stereoselective total syntheses of the antitumor antibiotics (+)-actinobolin and (-)-bactobolin from a common bridged lactone intermediate

Efficient, highly steroselective approaches have been developed to (+)-actinobolin (1) and (-)-bactobolin (3) from bridged α-keto lactone 11, which can be readily prepared via intramolecular SnCl4 catalyzed ene reaction of cyclohexenol glyoxyla

HIGHLY STEREOSELECTIVE SYNTHESIS OF ANTITUMOR ANTIBIOTICS, (+)-ACTINOBOLIN AND (-)-BACTOBOLIN, BY ASYMMETRIC CYCLIZATION

A common skeleton of (+)-actinobolin and (-)-bactobolin was efficiently formed by an intramolecular Diels-Alder reaction of a chiral Z diene with a substituent at the pentadienylic carbon, and the following transformation completed the first total synthes