88549-81-9

Upstream product

• 26367-48-6 fumaric acid ethyl ester mono chloride 
• 88549-80-8 Benzoic acid (Z)-(1R,2R)-2-amino-1-methyl-hexa-3,5-dienyl ester; hydrochloride 
• 88549-79-5 (4R,5R)-4-((E)-Buta-1,3-dienyl)-5-methyl-2-phenyl-4,5-dihydro-oxazole 
• 88549-78-4 Toluene-4-sulfonate((4S,5R)-5-methyl-2-phenyl-4,5-dihydro-oxazol-4-ylmethyl)-triphenyl-phosphonium; 

Downstream Products

• 88549-82-0 (1R,3aR,4R,7aR)-1-((R)-1-Benzyloxy-ethyl)-3-oxo-2,3,3a,4,5,7a-hexahydro-1H-isoindole-4-carboxylic acid ethyl ester 
• 88549-82-0 (1R,3aR,4R,7aR)-1-((R)-1-Benzoyloxy-ethyl)-3-oxo-2,3,3a,4,5,7a-hexahydro-1H-isoindole-4-carboxylic acid ethyl ester 
• 88549-91-1 N-((3R,4R,4aR,5R,6R,8aS)-5,6-Dihydroxy-3-methyl-8-methylene-1-oxo-octahydro-isochromen-4-yl)-C-p-tolyl-methanesulfonamide 
• 88549-90-0 N-((3R,4R,4aR,5R,6R,8R,8aS)-5,6-Dihydroxy-3-methyl-1-oxo-8-phenylselanylmethyl-octahydro-isochromen-4-yl)-C-p-tolyl-methanesulfonamide 
• 88549-89-7 (3R,3aR,4R,5R,7R,7aR)-4,5-Dihydroxy-3-((R)-1-hydroxy-ethyl)-7-phenylselanylmethyl-2-p-tolylmethanesulfonyl-octahydro-isoindol-1-one 
• 88549-88-6 (3aR,5R,5aR,8R,8aR,8bR)-2,2-Dimethyl-5-phenylselanylmethyl-8-[(R)-1-(tetrahydro-pyran-2-yloxy)-ethyl]-octahydro-[1,3]dioxolo[4,5-e]isoindol-6-one 
• 88549-92-2 C-p-Tolyl-N-((3R,4R,4aR,5R,6R)-5,6,8-trihydroxy-3-methyl-1-oxo-3,4,4a,5,6,7-hexahydro-1H-isochromen-4-yl)-methanesulfonamide 
• 88549-95-5 N-Cbz-actinobolin 

Relevant academic research and scientific papers

HIGHLY STEREOSELECTIVE SYNTHESIS OF ANTITUMOR ANTIBIOTICS, (+)-ACTINOBOLIN AND (-)-BACTOBOLIN, BY ASYMMETRIC CYCLIZATION

A common skeleton of (+)-actinobolin and (-)-bactobolin was efficiently formed by an intramolecular Diels-Alder reaction of a chiral Z diene with a substituent at the pentadienylic carbon, and the following transformation completed the first total synthes