885672-81-1 Usage
Description
[1,1'-Biphenyl]-4-carboxamide, N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]is a complex organic molecule that belongs to the class of carboxamide derivatives. It features a biphenyl core structure with a 4-chlorophenyl group and a dimethylamino propyl group attached to the carboxamide nitrogen. This unique structure and potential reactivity make it a compound of interest for various applications.
Uses
Used in Pharmaceutical Applications:
[1,1'-Biphenyl]-4-carboxamide, N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]is used as a pharmaceutical compound for its potential therapeutic properties. Its unique structure may allow it to interact with specific biological targets, making it a candidate for the development of new drugs.
Used in Materials Science:
In the field of materials science, [1,1'-Biphenyl]-4-carboxamide, N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]is used as a component in the development of new materials. Its structural characteristics may contribute to the creation of materials with specific properties, such as improved strength, flexibility, or chemical resistance.
Used in Chemical Research:
[1,1'-Biphenyl]-4-carboxamide, N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]is also used in chemical research as a subject for further study and analysis. Understanding its properties and reactivity can provide valuable insights into its potential applications and uses in various industries.
Please note that the specific applications and uses mentioned above are hypothetical and based on the general properties of the compound. Further research and development would be required to confirm these applications and to develop the compound for practical use.
Check Digit Verification of cas no
The CAS Registry Mumber 885672-81-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,6,7 and 2 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 885672-81:
(8*8)+(7*8)+(6*5)+(5*6)+(4*7)+(3*2)+(2*8)+(1*1)=231
231 % 10 = 1
So 885672-81-1 is a valid CAS Registry Number.
885672-81-1Relevant articles and documents
Novel and potent small-molecule urotensin II receptor agonists
Lehmann, Fredrik,Currier, Erika A.,Clemons, Bryan,Hansen, Lars K.,Olsson, Roger,Hacksell, Uli,Luthman, Kristina
experimental part, p. 4657 - 4665 (2009/12/06)
A series of analogs of the non-peptidic urotensin II receptor agonist N-[1-(4-chlorophenyl)-3-(dimethylamino)propyl]-4-phenylbenzamide (FL104) has been synthesized and evaluated pharmacologically. The enantiomers of the two most potent racemic analogues were obtained from the corresponding diastereomeric mandelic amides. In agreement with previously observed SAR, most of the agonist potency resided in the (S) enantiomers. The most potent UII receptor agonist in the new series was (S)-N-[3-dimethylamino-1-(2-naphthyl)propyl]-4-(4-chlorophenyl)benzamide (EC50 = 23 nM at the urotensin II receptor).
Novel potent and efficacious nonpeptidic urotensin II receptor agonists
Lehmann, Fredrik,Pettersen, Anna,Currier, Erika A.,Sherbukhin, Vladimir,Olsson, Roger,Hacksell, Uli,Luthman, Kristina
, p. 2232 - 2240 (2007/10/03)
Six different series of nonpeptidic urotensin II receptor agonists have been synthesized and evaluated for their agonistic activity in a cell-based assay (R-SAT). The compounds are ring-opened analogues of the isochromanone-based agonist AC-7954 with different functionalities constituting the linker between the two aromatic ring moieties. Several of the compounds are highly potent and efficacious, with N-[1-(4-chlorophenyl)-3-(dimethylamino)- propyl]-4-phenylbenzamide oxalate (5d) being the most potent. The pure enantiomers of 5d were obtained from the corresponding diastereomeric amides. It was shown by a combination of X-ray crystallography and chemical correlation that the activity resides in the S-enantiomer of 5d (pEC50 7.49).
