88568-96-1

Upstream product

• 152972-11-7 Z-AIB-(L)-Phe-(D)-Pro-OMe 
• 2577-48-2 D-Pro-OMe 
• 1138156-33-8 Boc-Aib-Phe-OH 
• 192057-94-6 2-(tert-butoxycarbonylamino)isobutyryl-L-phenylalanine methyl ester 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 
• 152972-10-6 Z-AIB-(L)-Phe-O-(t-Bu) 

Downstream Products

• 339061-50-6 methyl N[2-({(2S,8E)-2-[(tert-butoxycarbonyl)amino]dec-8-enoyl}amino)-2-methylpropanoyl]-L-phenylalanyl-D-prolinate 
• 88643-73-6 chlamydocin 
• 152972-13-9 (R)-1-{(S)-2-[2-((S)-2-Benzyloxycarbonylamino-5-chloro-pentanoylamino)-2-methyl-propionylamino]-3-phenyl-propionyl}-pyrrolidine-2-carboxylic acid pentafluorophenyl ester 
• 108072-00-0 cyclo<(2(γ)-Amino-10-chloro-8(S),9(R)-dihydroxydecanoyl)-dimethylglycyl-(S)-phenylalanyl-(R)-prolyl> 
• 1138156-34-9 C₃₄H₅₀N₄O₈ 
• 88643-73-6 epi-chlamydocin 
• 52574-63-7 (5S,11S,13aR)-5-Benzyl-8,8-dimethyl-11-(6-oxo-oct-7-enyl)-decahydro-3a,6,9,12-tetraaza-cyclopentacyclododecene-4,7,10,13-tetraone 
• 104849-05-0 cyclo[2-aminoisobutyryl-(S)-phenylalanyl-(R)-prolyl-(S)-2-aminosuberoyl-] 

Relevant academic research and scientific papers

Divergent Access to Histone Deacetylase Inhibitory Cyclopeptides via a Late-Stage Cyclopropane Ring Cleavage Strategy. Short Synthesis of Chlamydocin

A unified step-economical strategy for accessing histone deacetylase inhibitory peptides is proposed, based on the late-stage installation of multiple zinc-binding functionalities via the cleavage of the strained cyclopropane ring in the common pluripoten

Stereospecific synthesis of chlamydocin

A stereospecific synthesis of the cyclic tetrapeptide chlamydocin via free radical homologation from a (S)-2-amino-5-iodopentanoic acid containing cyclic tetrapeptide is described.

Synthesis of the cytostatic cyclic tetrapeptide, chlamydocin

Chlamydocin has been synthesized by a route utilizing allylic hydroxylation and epoxidation of the DL-2-amino-9-decenoic acid residue to form the 2-amino-8-oxo-9,10-epoxydecanoic acid residue.