88574-54-3Relevant academic research and scientific papers
A practical method for the aziridination of α,β-unsaturated carbonyl compounds with a simple carbamate utilizing sodium hypochlorite pentahydrate
Minakata, Satoshi,Umeda, Takehiro
, p. 22120 - 22124 (2021/07/02)
The efficient formation oftert-butylN-chloro-N-sodio-carbamate by the reaction of simpletert-butyl carbamate with sodium hypochlorite pentahydrate (NaOCl·5H2O) would be a practical and green method for the aziridination of α,β-unsaturated carbo
Novel water-soluble prodrugs
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Page/Page column 145; 146, (2017/04/25)
The present invention provides compounds represented by formula (1A), or pharmaceutically acceptable salts. Compounds represented by formula (1A), or pharmaceutically acceptable salts thereof, wherein A 1 and A 2 are identical or different, and each indep
A multicatalyst system for the one-pot desymmetrization/oxidation of meso-1,2-alkane diols
Mueller, Christian E.,Hrdina, Radim,Wende, Raffael C.,Schreiner, Peter R.
supporting information; experimental part, p. 6309 - 6314 (2011/08/07)
Two is better than one: We demonstrate the viability of an organocatalytic reaction sequence along a short peptide backbone that carries two independent catalytic functionalities, which allow the rapid, one-pot acylative desymmetrization and oxidation of meso-alkane-1,2-diols to the corresponding acetylated acetoins with good yields and enantioselectivities (see scheme). Copyright
MIMETIC COMPOSITIONS AND THE PRODUCTION THEREOF
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Page/Page column 27, (2010/09/05)
The present invention generally relates to compositions including six membered heterocyclic 1,4-diaza-2-one moieties covalently bonded by a hydrazine bond and processes for producing the same. The compositions of the present invention may be utilized as p
In vitro efficiency of new acridyl derivatives against Plasmodium falciparum
Guetzoyan, Lucie,Ramiandrasoa, Florence,Dorizon, Helene,Desprez, Christine,Bridoux, Alexandre,Rogier, Christophe,Pradines, Bruno,Perree-Fauvet, Martine
, p. 3278 - 3289 (2008/02/07)
A series of new 9-substituted acridyl derivatives were synthesized and their in vitro antimalarial activity was evaluated against one chloroquine-sensitive strain (3D7) and three chloroquine-resistant strains [W2 (Indochina), Bre1 (Brazil) and FCR3 (Gambi
Urethane N-carboxyanhydrides from β-amino acids
McKiernan,Huck,Fehrentz,Roumestant,Viallefont,Martinez
, p. 6541 - 6544 (2007/10/03)
A general method has been developed for the synthesis of N-tert-butyloxycarbonyl N-carboxyanhydrides from β-amino acids using Vilsmeier complex. These β-UNCA are stable, and the reactivity with different nucleophiles (alcohol, amine, lithium enolate) was studied.
Structural features resulting in convulsive activity of carbapenem compounds: Effect of C-2 side chain
Sunagawa,Matsumura,Sumita,Nouda
, p. 408 - 416 (2007/10/02)
The neurotoxicity of meropenem was much lower than that of both imipenem and panipenem after intraventricular administration to mice. To clarify the major structural features responsible for the induction of convulsions by carbapenem antibiotics, the stru
