88588-30-1Relevant academic research and scientific papers
Iridium-catalyzed enantioselective hydrogenation of α,β- unsaturated carboxylic acids with tetrasubstituted olefins
Song, Song,Zhu, Shou-Fei,Li, Yu,Zhou, Qi-Lin
supporting information, p. 3722 - 3725 (2013/08/23)
A highly efficient asymmetric hydrogenation of α,β-unsaturated carboxylic acids with tetrasubstituted olefin catalyzed by chiral spiro iridium complexes has been developed for the preparation of chiral α-substituted carboxylic acids in excellent enantioselectivities (up to 99% ee).
Process-scale total synthesis of nature-identical (-)-(S,S)-7- hydroxycalamenal in high enantiomeric purity through catalytic enantioselective hydrogenation
Benincori, Tiziana,Bruno, Silvana,Celentano, Giuseppe,Pilati, Tullio,Ponti, Alessandro,Rizzo, Simona,Sada, Mara,Sannicolo, Francesco
, p. 1776 - 1789 (2007/10/03)
A process-scale stereoselective synthesis of nature-identical (-)-(S,S)-7-hydroxycalamenal (=(-)-(5S,85)-5,6,7,8-tetrahydro-3-hydroxy-5- methyl-8-(1-methylethyl)naphthalene-2-carbaldehyde; (-)-1α) in 96% enantiomeric excess (ee) with the aid of chiral Ru
Synthesis of Optically Active α-Isopropyl-4-substituted Phenylacetic Acids by Asymmetric Hydrogenation
Takemoto, Ichiki,Kawamura, Norio,Kaminaka, Hiroshi
, p. 2071 - 2072 (2007/10/02)
Homogeneous hydrogenation of 2-phenyl-3-methyl-2-butenoic acid derivatives in the presence of a catalytic amount of such chiral phosphine-rhodium complexes as Rh/(R)-BINAP, Rh/(R)-, or (S)-Cy-BINAP, Rh/(R)-p-tolyl-BINAP, and Rh/(R)-p-methoxyphenyl-BINAP afforded the corresponding phenylacetic acid derivatives in high enantiomeric excesses and in quantitative chemical yields.The optically activa phenylacetic acid derivatives are useful intermediates of agrochemicals and pharmaceuticals.
ENZYMATIC RESOLUTION OF METHYL 2-ALKYL-2-ARYLACETATES
Ahmar, M.,Girard, C.,Bloch, R.
, p. 7053 - 7056 (2007/10/02)
Horse liver esterase, used as its inexpensive commercial acetone powder, catalyzes the selective hydrolysis of methy 2-alkyl-2-arylacetates to afford R(-)-2-alkyl-2-arylacetic acids and S(+)-methyl 2-alkyl-2-arylacetates.
