885953-27-5 Usage
General Description
3-Methyl-pyrrolidine-3-carboxylic acid is a chemical compound with a molecular formula of C7H13NO2. It is a derivative of pyrrolidine and is commonly used in the pharmaceutical industry as a building block for the synthesis of various drugs and pharmaceutical products. 3-Methyl-pyrrolidine-3-carboxylic acid has a pyrrolidine ring with a methyl group attached to it, as well as a carboxylic acid group. It has the potential to exhibit biological activity and may have applications in the development of new medications. Its structural properties make it a valuable intermediate in organic synthesis, particularly in the production of pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 885953-27-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,9,5 and 3 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 885953-27:
(8*8)+(7*8)+(6*5)+(5*9)+(4*5)+(3*3)+(2*2)+(1*7)=235
235 % 10 = 5
So 885953-27-5 is a valid CAS Registry Number.
InChI:InChI=1/C6H11NO2/c1-6(5(8)9)2-3-7-4-6/h7H,2-4H2,1H3,(H,8,9)
885953-27-5Relevant articles and documents
Asymmetric synthesis and catalytic activity of 3-methyl-β-proline in enantioselective anti -mannich-type reactions
Nagata, Kazuhiro,Kuga, Yasushi,Higashi, Akinori,Kinoshita, Atsushi,Kanemitsu, Takuya,Miyazaki, Michiko,Itoh, Takashi
, p. 7131 - 7136 (2013/08/23)
Enantiomerically pure 3-methyl-β-proline was synthesized using an asymmetric phase-transfer-catalyzed alkylation of a cyanopropanoate to establish the all-carbon stereogenic center. The catalytic activity of 3-methyl-β-proline in the Mannich-type reaction between a glyoxylate imine and ketones/aldehydes was subsequently investigated. The catalyst was designed and found to be more soluble in nonpolar organic solvents relative to the unsubstituted β-proline catalyst, and as a result allowed for added flexibility during optimization efforts. This work culminated in the development of a highly anti-diastereo- and enantioselective process employing low catalyst loading.
