88612-00-4 Usage
Uses
Used in Pharmaceutical Industry:
3,4-Dihydro-1-isoquinolinecarboxylic acid ethyl ester is used as a key intermediate in the synthesis of various bioactive compounds and pharmaceutical drugs. Its unique structural features allow for the development of new therapeutic agents with potential applications in treating a wide range of diseases and conditions.
Used in Medicinal Chemistry Research:
3,4-Dihydro-1-isoquinolinecarboxylic acid ethyl ester is used as a valuable building block in medicinal chemistry research. Its structural properties enable the design and development of innovative therapeutic agents with improved pharmacological properties, such as enhanced efficacy, selectivity, and reduced side effects.
Used in Drug Discovery and Development:
3,4-Dihydro-1-isoquinolinecarboxylic acid ethyl ester is employed in drug discovery and development processes to identify and optimize new drug candidates. Its unique structural features and potential biological activity make it a promising starting point for the development of novel therapeutic agents with improved pharmacological profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 88612-00-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,6,1 and 2 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 88612-00:
(7*8)+(6*8)+(5*6)+(4*1)+(3*2)+(2*0)+(1*0)=144
144 % 10 = 4
So 88612-00-4 is a valid CAS Registry Number.
88612-00-4Relevant academic research and scientific papers
METHOD FOR PRODUCING BENZAZEPINONE
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Page/Page column 16, (2008/12/04)
It is an object of the present invention to provide 2-iminocarboxylic acid derivatives, and a practically suitable industrial method for producing benzazepinones in a short process under mild conditions. The present invention provides a method for producing a benzazepinone or a salt thereof, which comprises opening a ring of an isoquinoline derivative and subsequently converting the thus generated amine into a benzazepinone through lactamization reaction.
A novel synthesis of isoquinolines containing an electron withdrawing substituent
Kohno, Harumichi,Yamada, Koichiro
, p. 103 - 117 (2007/10/03)
3,4-Dihydroisoquinolines (10, 13) and isoquinolines (11), having various electron withdrawing substituent were synthesized in two steps from N- benzenesulfonyl- or N, N-dimethylsulfamoyl-β-phenethylamines (2 and 5). A novel cyclization method using ethyl chloro(methylthio)acetate (1) in the presence of SnCl4 as Lewis acid, followed by acid or base treatment provides the title compounds in good yield.
