886226-24-0

Basic information

• Product Name: retinal tert-butyl-dimethylsilylcyanohydrin
• Synonyms: retinal tert-butyl-dimethylsilylcyanohydrin
• CAS NO: 886226-24-0
• Molecular Weight: 425.73
• Mol File: 886226-24-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: retinal tert-butyl-dimethylsilylcyanohydrin(CAS DataBase Reference)
• NIST Chemistry Reference: retinal tert-butyl-dimethylsilylcyanohydrin(886226-24-0)
• EPA Substance Registry System: retinal tert-butyl-dimethylsilylcyanohydrin(886226-24-0)

Safety Data

• Hazardous Substances Data: 886226-24-0(Hazardous Substances Data)

Upstream product

• 116-31-4 all-trans-Retinal 
• 56522-24-8 tert-butyldimethylsilyl cyanide 

Downstream Products

• 886226-26-2 2,6-anhydro-7-deoxy-7-[4-(retinoylmethyl)phenyl]-3,4,5-tri-O-acetyl-L-glycero-L-gulo-heptonic acid methyl ester 
• 886226-25-1 (2S,3S,4R,5S,6S)-3,4,5-Triacetoxy-6-{4-[(3E,5E,7E,9E)-2-(tert-butyl-dimethyl-silanyloxy)-2-cyano-4,8-dimethyl-10-(2,6,6-trimethyl-cyclohex-1-enyl)-deca-3,5,7,9-tetraenyl]-benzyl}-tetrahydro-pyran-2-carboxylic acid methyl ester 

Relevant articles and documents

Synthesis and preliminary chemotherapeutic evaluation of the fully C-linked glucuronide of N-(4-hydroxyphenyl)retinamide

All-trans retinoic acid analogues such as N-(4-hydroxyphenyl)retinamide (4-HPR) are effective chemopreventive and chemotherapeutic agents but their utility has been hampered by dose-limiting side effects. The glucuronide derivatives of 4-HPR, the oxygen-l

C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and method of using the same to inhibit neoplastic cell growth

Compounds of the formula: are described, along with pharmaceutical compositions containing these compounds, and methods of using the compounds to prevent and to treat cancer in mammals, including humans.