886226-25-1Relevant articles and documents
C-linked glucuronide of N-(4-hydroxybenzyl) retinone, analogs thereof, and method of using the same to inhibit neoplastic cell growth
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Page/Page column 5; 11, (2008/06/13)
Compounds of the formula: are described, along with pharmaceutical compositions containing these compounds, and methods of using the compounds to prevent and to treat cancer in mammals, including humans.
Synthesis and preliminary chemotherapeutic evaluation of the fully C-linked glucuronide of N-(4-hydroxyphenyl)retinamide
Walker, Joel R.,Alshafie, Galal,Nieves, Nirca,Ahrens, Jamie,Clagett-Dame, Margaret,Abou-Issa, Hussein,Curley Jr., Robert W.
, p. 3038 - 3048 (2007/10/03)
All-trans retinoic acid analogues such as N-(4-hydroxyphenyl)retinamide (4-HPR) are effective chemopreventive and chemotherapeutic agents but their utility has been hampered by dose-limiting side effects. The glucuronide derivatives of 4-HPR, the oxygen-l