88636-66-2Relevant articles and documents
Efficient resolution of rac-2-cyano-2-methyl-3-phenylpropanoic acid. An appropriate starting material for the enantioconvergent synthesis of (S)-α-methylphenylalanine on a large laboratory scale
Badorrey, Ramon,Cativiela, Carlos,Diaz-de-Villegas, Maria D.,Galvez, Jose A.
, p. 2201 - 2207 (2003)
A large laboratory scale synthesis of (S)-α-methylphenylalanine from benzaldehyde and methyl cyanoacetate has been developed. The synthesis is based on the following sequence: (i) preparation of racemic 2-cyano-2-methyl-3-phenylpropanoic acid, (ii) resolu