61137-36-8

Basic information

• Product Name: 2,5-Oxazolidinedione, 4-methyl-4-(phenylmethyl)-
• Synonyms: 2,5-Oxazolidinedione, 4-methyl-4-(phenylmethyl)-
• CAS NO: 61137-36-8
• Molecular Formula: C11H11NO3
• Molecular Weight: 205.21
• Mol File: 61137-36-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,5-Oxazolidinedione, 4-methyl-4-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Oxazolidinedione, 4-methyl-4-(phenylmethyl)-(61137-36-8)
• EPA Substance Registry System: 2,5-Oxazolidinedione, 4-methyl-4-(phenylmethyl)-(61137-36-8)

Safety Data

• Hazardous Substances Data: 61137-36-8(Hazardous Substances Data)

Usage

Type of Compound

Heterocyclic compound

Structure

Five-membered ring with oxygen and nitrogen atoms

Usage

Synthesis of pharmaceuticals and other organic compounds

Common Applications

Production of antiepileptic drugs

Potential Properties

Anticonvulsant

Role in Chemistry

Reagent in organic chemistry reactions, particularly in the formation of carbon-carbon bonds

Fields of Study

Medicinal chemistry and drug discovery.

Upstream product

• 79-37-8 oxalyl dichloride 
• 159835-31-1 (R)-α-benzyl-α-methylmalonamic acid 
• 108211-28-5 (R)-(-)-2-cyano-2-methyl-3-phenylpropionic acid 
• 41864-05-5 2-cyano-2-methyl-3-phenylpropanoic acid 
• 88636-66-2 methyl 2-cyano-2-methyl-3-phenylpropanoate 
• 14533-86-9 methyl (E)-2-cyano-3-phenylprop-2-enoate 
• 57519-78-5 methyl 2-cyano-4-phenylpropanoate 

Relevant articles and documents

A PROCESS FOR RESOLVING RACEMIC MIXTURES AND A DIASTEREOISOMERIC COMPLEX OF A RESOLVING AGENT AND AN ENANTIOMER OF INTEREST

A process for resolving a compound in racemic form comprising the following steps is described: a) reacting a compound in racemic form with a resolving agent, b) forming a diastereoisomeric complex of the resolving agent and an enantiomer of interest, c} separating the enantiomer of interest from the obtained diastereoisomer, wherein such a process is characterized in that said resolving agent is a compound of Formula (I). A diastereoisomeric complex between the resolving agent of Formula (I) and the enantiomer of interest is also described. The process according to the invention allows acid and basic racemic mixtures to be separated.

Efficient resolution of rac-2-cyano-2-methyl-3-phenylpropanoic acid. An appropriate starting material for the enantioconvergent synthesis of (S)-α-methylphenylalanine on a large laboratory scale

A large laboratory scale synthesis of (S)-α-methylphenylalanine from benzaldehyde and methyl cyanoacetate has been developed. The synthesis is based on the following sequence: (i) preparation of racemic 2-cyano-2-methyl-3-phenylpropanoic acid, (ii) resolu

The design and synthesis of 2,5-linked pyrrolinones. A potential non- peptide peptidomimetic scaffold

The de novo design and initial synthetic studies directed toward construction of a novel non-peptide scaffold for β-strand/sheet and related secondary peptide structural mimics are described. The scaffold, consisting of a repeating array of 2,5,5-trisubstituted pyrrolinone (enaminone) units punctuated with appropriate amino acid side chains, is conceptually related to our previously successful 3,5-linked polypyrrolinone non-peptide peptidomimetic scaffold. Construction of the 2,5,5-trisubstituted pyrrolinone ring system proceeds via intramolecular condensation of an N-protected amino dione. The latter is prepared from a protected α-amino ketone and aldehyde via an aldol-oxidation reaction sequence.