886364-47-2

Basic information

• Product Name: 1-(6-BROMO-PYRIDIN-3-YL)-2,2,2-TRIFLUORO-ETHANONE
• Synonyms: 1-(6-BROMO-PYRIDIN-3-YL)-2,2,2-TRIFLUORO-ETHANONE;1-(6-bromopyridin-3-yl)-2,2,2-trifluoroethane-1,1-diol
• CAS NO: 886364-47-2
• Molecular Formula: C7H3BrF3NO
• Molecular Weight: 254.0040296
• Mol File: 886364-47-2.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 1-(6-BROMO-PYRIDIN-3-YL)-2,2,2-TRIFLUORO-ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-BROMO-PYRIDIN-3-YL)-2,2,2-TRIFLUORO-ETHANONE(886364-47-2)
• EPA Substance Registry System: 1-(6-BROMO-PYRIDIN-3-YL)-2,2,2-TRIFLUORO-ETHANONE(886364-47-2)

Safety Data

• Hazardous Substances Data: 886364-47-2(Hazardous Substances Data)

Usage

General Description

1-(6-Bromo-pyridin-3-yl)-2,2,2-trifluoro-ethanone is a chemical compound with the molecular formula C7H4BrF3NO. It is a yellow solid that is used as a building block in the production of various pharmaceuticals and agrochemicals. 1-(6-BROMO-PYRIDIN-3-YL)-2,2,2-TRIFLUORO-ETHANONE is a ketone derivative with a trifluoromethyl group and a bromopyridine group, which makes it useful in the synthesis of diverse chemical compounds. 1-(6-Bromo-pyridin-3-yl)-2,2,2-trifluoro-ethanone is also used as a reagent in organic synthesis and is known for its potential biological activities.

Upstream product

• 624-28-2 2,5-dibromopyridine 
• 360-95-2 2,2,2-Trifluoro-1-morpholin-4-yl-ethanone 
• 26218-78-0 methyl 6-bromonicotinate 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 1188477-81-7 1-(6-bromopyridin-3-yl)-2,2,2-trifluoroethanol 
• 149806-06-4 6-bromonicotinaldehyde 

Downstream Products

• 1188477-89-5 1-(6-cyanopyridin-3-yl)-2,2,2-trifluoroethyl 4-methylbenzenesulfonate 
• 1188477-81-7 1-(6-bromopyridin-3-yl)-2,2,2-trifluoroethanol 
• 1450620-92-4 benzyl (3S)-4-(5-(2,2-dimethyl-4-(trifluoromethyl)-1,3-dioxolan-4-yl)-2-pyridinyl)-3-(1-propyn-1-yl)-1-piperazinecarboxylate 

Relevant articles and documents

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Highly efficient synthesis of aryl and heteroaryl trifluoromethyl ketones via o-iodobenzoic acid (IBX)

A two-step process for the synthesis of aryl and heteroaryl trifluoromethyl ketones from the corresponding aldehydes is described. Trifluoromethyl alcohols were prepared from aryl and heteroaryl aldehydes in excellent yields using catalytic amount of K2CO3. The trifluoromethyl alcohols were then oxidized conveniently and efficiently by o-iodoxybenzoic acid (IBX) under mild conditions to get the desired functionalized aryl and heteroaryl trifluoromethyl ketones.