886368-96-3

Upstream product

• 134665-70-6 (Z)-3-((2R,4R)-2-Phenyl-[1,3]dioxan-4-yl)-acrylic acid methyl ester 
• 108-98-5 thiophenol 
• 886368-32-7 1-phenylsulfonyl-3-(phenylthio)propane 
• 886368-27-0 (2R,4R)-4-((Z)-3-Bromo-propenyl)-2-phenyl-[1,3]dioxane 
• 886369-22-8 (Z)-3-((2R,4R)-2-Phenyl-[1,3]dioxan-4-yl)-prop-2-en-1-ol 
• 67-56-1 methanol 
• 3238-98-0 3-phenylthio-1-bromopropane 

Downstream Products

• 886368-17-8 {2-[6-(2-benzenesulfonyl-ethyl)-6-methoxy-5,6-dihydro-2H-pyran-2-yl]-ethoxy}-tert-butyl-diphenyl-silane 

Relevant academic research and scientific papers

Synthesis of the C1-C26 northern portion of azaspiracid-1: Kinetic versus thermodynamic control of the formation of the bis-spiroketal

North-South divide: An efficient synthesis of the entire C1-C26 (northern) portion of azaspiracid-1 is disclosed (see picture). Key transformations include the formation of a bis-spiroketal, the oxidation of a sulfone at C10 to form a β,γ-unsaturated keto