88644-06-8

Upstream product

• 82414-47-9 (E)-(2S,3R)-3-Methoxy-2-methyl-5-phenyl-pent-4-enoic acid methyl ester 
• 82414-51-5 (E)-(2S,3S)-2-Methyl-5-phenyl-pent-4-ene-1,3-diol 
• 74-88-4 methyl iodide 
• 14371-10-9 (E)-3-phenylpropenal 
• 910131-70-3 (-)-(4R,5S)-3-(E-(2R,3S)-3-methoxy-2-methyl-5-phenyl-pent-4-enoyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 138694-16-3 (4R,5S)-3-<(2R,3R,4E)-3-Hydroxy-2-methyl-5-phenyl-4-pentenoyl>-4-methyl-5-phenyl-2-oxazolidinone 
• 86853-06-7 Methyl 2-methyl-3-oxo-5-phenyl-4-pentenoate 
• 67498-12-8 (E)-syn-methyl 3-hydroxy-2-methyl-5-phenyl-4-pentanoate 
• 67498-12-8 (E)-(2S,3S)-3-Hydroxy-2-methyl-5-phenyl-pent-4-enoic acid methyl ester 

Downstream Products

• 910131-53-2 (+)-E-(2R,3S)-5-methoxy-4-methyl-3-oxo-7-phenyl-hept-6-enoic acid methyl ester 
• 478011-19-7 (+)-E-2,E-6-(4R,5S)-3,5-dimethoxy-4-methyl-7-phenyl-hepta-2,6-dienoic acid methyl ester 
• 73341-71-6 oudemansin A 
• 73341-71-6 (+/-)-oudemansin A 
• 88155-83-3 methyl (E)-(3R^*,4S^*)-4-methoxy-3-methyl-6-phenylhexa-5-enoate 

Relevant academic research and scientific papers

Total synthesis of myxothiazols, novel bis-thiazole β-methoxyacrylate- based anti-fungal compounds from myxobacteria

Convergent total syntheses of myxothiazols A and Z are described. The syntheses are based on elaboration of the (S)-E,E-diene thioamide 22, conversion of 22 into the bis-thiazole 27 and Wittig reactions between 27c and the aldehyde 30. The substituted β-m