910131-70-3

Upstream product

• 138694-16-3 (4R,5S)-3-<(2R,3R,4E)-3-Hydroxy-2-methyl-5-phenyl-4-pentenoyl>-4-methyl-5-phenyl-2-oxazolidinone 
• 333-27-7 methyl trifluoromethanesulfonate 
• 14371-10-9 (E)-3-phenylpropenal 
• 77877-20-4 (4R,5S)-4-methyl-5-phenyl-3-propionyloxazolidin-2-one 

Downstream Products

• 88644-06-8 (+)-E-(2R,3S)-3-methoxy-2-methyl-5-phenyl-pent-4-enoic acid 
• 478011-19-7 (+)-E-2,E-6-(4R,5S)-3,5-dimethoxy-4-methyl-7-phenyl-hepta-2,6-dienoic acid methyl ester 
• 910131-53-2 (+)-E-(2R,3S)-5-methoxy-4-methyl-3-oxo-7-phenyl-hept-6-enoic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis of myxothiazols, novel bis-thiazole β-methoxyacrylate- based anti-fungal compounds from myxobacteria

Convergent total syntheses of myxothiazols A and Z are described. The syntheses are based on elaboration of the (S)-E,E-diene thioamide 22, conversion of 22 into the bis-thiazole 27 and Wittig reactions between 27c and the aldehyde 30. The substituted β-m