886449-70-3

Basic information

• Product Name: tert-butyl 7-benzyl-6-oxo-1,7-diazaspiro[4.4]nonane-1-carboxylate
• CAS NO: 886449-70-3
• Molecular Formula: C₁₉H₂₆N₂O₃
• Molecular Weight: 330.42
• Mol File: 886449-70-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 497.3°C at 760 mmHg
• Flash Point: 254.6°C
• Density: 1.18g/cm³
• Vapor Pressure: 4.99E-10mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: tert-butyl 7-benzyl-6-oxo-1,7-diazaspiro[4.4]nonane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 7-benzyl-6-oxo-1,7-diazaspiro[4.4]nonane-1-carboxylate(886449-70-3)
• EPA Substance Registry System: tert-butyl 7-benzyl-6-oxo-1,7-diazaspiro[4.4]nonane-1-carboxylate(886449-70-3)

Safety Data

• Hazardous Substances Data: 886449-70-3(Hazardous Substances Data)

Upstream product

• 147-85-3 L-proline 
• 112348-45-5 1-tert-butyl 2-methyl 2-(prop-2-en-1-yl)pyrrolidine-1,2-dicarboxylate 
• 59936-29-7 (S)-N-(tert-butoxycarbonyl)proline methyl ester 
• 2577-48-2 methyl (2S)-pyrrolidine carboxylate 
• 850426-34-5 1-tert-butyl 2-methyl 2-(2-oxoethyl)pyrrolidine-1,2-dicarboxylate 

Relevant articles and documents

Spirobicyclic diamines. Part 3: Synthesis and metal complexation of proline-derived [4.4]-spirodiamines

The syntheses of racemic and homochiral [4.4]-spirolactams, starting from l-proline, in good yields are described. Reduction of the lactam carbonyl group of spirolactams, containing chiral substituents on the lactam nitrogen, with lithium aluminium hydride, gives?a series of homochiral [4.4]-spirodiamines. The crystal structure of one of these spirodiamines on complexation with zinc chloride was obtained. Interestingly it showed a hydrogen-bonded dimeric structure, where the monomers are diastereoisomeric diamines.