88670-06-8

Basic information

• Product Name: Carbonic acid 5-[(5R,6S)-3-(2-cyano-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-en-2-yl]-tetrazol-1-ylmethyl ester 4-nitro-benzyl ester
• Synonyms: Carbonic acid 5-[(5R,6S)-3-(2-cyano-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-en-2-yl]-tetrazol-1-ylmethyl ester 4-nitro-benzyl ester
• CAS NO: 88670-06-8
• Molecular Weight: 515.506
• Mol File: 88670-06-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Carbonic acid 5-[(5R,6S)-3-(2-cyano-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-en-2-yl]-tetrazol-1-ylmethyl ester 4-nitro-benzyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbonic acid 5-[(5R,6S)-3-(2-cyano-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-en-2-yl]-tetrazol-1-ylmethyl ester 4-nitro-benzyl ester(88670-06-8)
• EPA Substance Registry System: Carbonic acid 5-[(5R,6S)-3-(2-cyano-ethylsulfanyl)-6-((R)-1-hydroxy-ethyl)-7-oxo-1-aza-bicyclo[3.2.0]hept-2-en-2-yl]-tetrazol-1-ylmethyl ester 4-nitro-benzyl ester(88670-06-8)

Safety Data

• Hazardous Substances Data: 88670-06-8(Hazardous Substances Data)

Upstream product

• 88670-05-7 (3S,4R)-1-(tert-butyldimethylsilyl)-3-<(R)-1-((tert-butyldimethylsilyl)oxy)ethyl>-4-<2-oxo-3-(tert-butoxycarbonyl)-3-(1-(((((p-nitrobenzyl)oxy)carbonyl)oxy)methyl)tetrazol-5-yl)propyl>azetidin-2-one 
• 88685-63-6 (3S,4R)-1-(tert-butyldimethylsilyl)-3-<(R)-1-hydroxyethyl>-4-<2-oxo-3-(5-(1-((((p-nitrobenzyl)oxy)carbonyl)oxy)methyl)tetrazolyl)propyl>azetidin-2-one 
• 88669-76-5 tert-butyl (1-(((((p-nitrobenzyl)oxy)carbonyl)oxy)methyl)tetrazol-5-yl)acetate 
• 88670-04-6 (3S,4R)-1-tert-butyldimethylsilyl-3-<(R)-2-((tert-butyldimethylsilyl)oxy)ethyl>-2-oxo-azetidin-4-acetic acid 
• 88728-84-1 (3S,4R)-1-(tert-butyldimethylsilyl)-3-<(R)-1-((tert-butyldimethylsilyl)oxy)ethyl>azetidin-2-one-4-acetyl chloride 
• 50780-46-6 ((((p-nitrobenzyl)oxy)carbonyl)oxy)methyl chloride 
• 1001-58-7 3-mercaptopropionitrile 
• 88669-85-6 (3S,4R)-3-<(R)-1-hydroxyethyl>-4-<2-oxo-3-(1-(((((p-nitrobenzyl)oxy)carbonyl)oxy)methyl)tetrazol-5-yl)propyl>azetidin-2-one 

Relevant articles and documents

Total Synthesis of 3-(5-Tetrazolyl)carbapenems

The synthesis of the title compounds, β-lactam antibiotics, is described.A new tetrazole protecting group, (((p-nitrobenzyl)carbonyl)oxy)methyl, was succesfully applied.Substitution of carboxyl by tetrazole on the carbapenem nucleus results in stability to a degradative renal enzyme.