88682-29-5

Basic information

• Product Name: 1,4-Benzenedimethanol, a-phenyl-
• CAS NO: 88682-29-5
• Molecular Formula: C14H14O2
• Molecular Weight: 214.264
• Mol File: 88682-29-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1,4-Benzenedimethanol, a-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Benzenedimethanol, a-phenyl-(88682-29-5)
• EPA Substance Registry System: 1,4-Benzenedimethanol, a-phenyl-(88682-29-5)

Safety Data

• Hazardous Substances Data: 88682-29-5(Hazardous Substances Data)

Upstream product

• 611-95-0 4-carboxybenzophenone 
• 52010-97-6 4-(hydroxylmethyl)benzaldehyde 
• 98-80-6 phenylboronic acid 
• 623-27-8 terephthalaldehyde, 
• 873-75-6 4-bromobenzenemethanol 
• 100-52-7 benzaldehyde 
• 87736-74-1 4-(tert-butyldimethylsiloxymethyl)bromobenzene 
• 134-84-9 4-Methylbenzophenone 
• 873-76-7 para-Chlorobenzyl alcohol 
• 20912-50-9 4-benzoylbenzaldehyde 

Downstream Products

• 81449-01-6 4-(hydroxymethyl)benzophenone 
• 20912-50-9 4-benzoylbenzaldehyde 
• 52010-95-4 4-(1-hydroxy-1-phenylmethyl)benzaldehyde 

Relevant articles and documents

Diarylmethanols synthesis by nickel(II)-catalyzed addition of arylboronic acids to aryl aldehydes

A practical procedure for the addition of arylboronic acids to aromatic aldehydes has been developed in the presence of NiCl2(PPh3)2/1,3-bis-(2,6-diisopropylphenyl)imidazolium chloride (IPr·HCl) system with good yield. Generally, electron-rich and-neutral aryl aldehydes showed excellent reactivity and provided desired products in high yields. This procedure will provide new way to the synthesis of diarylmethanols.

Chemoselective reduction of aldehydes: Via a combination of NaBH4 and acetylacetone

A bench-stable combination of NaBH4-acetylacetone was developed for the efficient chemoselective reduction of aldehydes in the presence of ketones. This method offers a useful synthetic protocol for distinguishing carbonyl reaction sites, and its synthetic utility is reflected by its moisture tolerance and high efficiency in a variety of complex settings.

An Efficient Ga(OTf)3/Isopropanol Catalytic System for Direct Reduction of Benzylic Alcohols

This study aims to report the first gallium-catalyzed direct reduction of benzylic alcohols using isopropanol as a reductant. The reaction proceeds via gallium catalyst-assisted hydride transfer of the in situ-generated benzylic isopropyl ether. The method generates only water and acetone as byproducts and thus provides an atom-economic and environmentally friendly approach to the synthesis of di- and triarylmethanes, which are important substructures in various bioactive compounds and functional materials. (Figure presented.).