88686-80-0Relevant academic research and scientific papers
Diastereoselective photochemical synthesis of 3,3'-disubstituted indolines
Ibrahim-Ouali, Malika,Sinibaldi, Marie-Eve,Troin, Yves,Guillaume, Dominique,Gramain, Jean-Claude
, p. 16083 - 16096 (2007/10/03)
Spiroindoline lactams 9 and imides 11 were efficiently and diastereoselectively prepared by photocyclization of N-arylenaminolactams 8 and esters 5 respectively. Imides 11 wee conveniently transformed into the known indolines 13 and 14 which are key intermediates for the synthesis of (±)-vindorosine and Aspidosperma alkaloids.
STEREOCONTROLLED FORMATION OF 1,2-DIHYDROINDOLES
Veenstra, S.J.,Fortgens, H.P.,Vijn, R.J.,Jong, B.S. de,Speckamp, W.N.
, p. 1147 - 1156 (2007/10/02)
Imines 4 cyclize stereoselectively to dihydroindoles 2 upon use of a Li or Na alkoxide-alcohol combination.Depending on the type of alcohol applied either cis (2C) or trans (2T) spiroindolines 2 are formed.In case of imines 4 derived from electron-rich ar
