88689-02-5

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 89-25-8 edaravone 
• 942-32-5 5-methyl-2-phenyl-2H-pyrazol-3-ol 
• 836-41-9 p-methoxybenzylidene-phenylamine 
• 223389-76-2 4-(4-methoxyphenyl)-3,5-dimethyl-1,7-diphenyl-4,7-dihydro-1H-pyrano[2,3-c:6,5-c']dipyrazole 
• 39143-07-2 4-anisylidene-3-methyl-1-phenylpyrazol-5-one 
• 30925-62-3 metochalcone 

Relevant academic research and scientific papers

Utility of 1-(2,4-dimethoxyphenyl)-3-aryl-prop-2-ene-1-ones as ring transformer in preparing heterocyclic compounds and their potential biological activities

As an effort to synthesize new heterocyclic compounds, which would be expected to have a pharmacological and biological activities, we report here the reactivity of 1-(2,4-dimethoxyphenyl)-3-aryl-2-propen-1-ones (Ia&b), as Michael acceptors under differen

New Aspects in the Reaction of Azomethines with Cyclic CH-Acidic Compounds

Treatment of substituted benzylidene anilines 1a - f with cyclic CH-acidic compounds 2a - m in ethanol at room temperature yields in addition/elimination reactions the corresponding arylidene derivatives 4 and the 2:1 adducts 5.The addition products 3, which are formed as intermediates, could not be isolated in any case.The donor/acceptor effect of the substituents on the benzylidene moiety influences to a significant extent the reactivity towards the azomethine carbon. Keywords.Azomethine; CH-Acidic compound; Addition/elimination reaction.

Investigations on the Hydrolytic Stability of 4-Arylmethylidene-2-pyrazolin-5-ones

The 4-Arylmethylidene-2-pyrazoline-5-ones S are not stable under aqueous alkaline conditions.By the substitution of R3 with electron donor substituents S reacts preferably yielding aldehyde A and 2-pyrazoline-5-one P, while with electron acceptor substituents S forms 4,4'-arylmethylidene-bis-2-pyrazoline-5-one B.The intermediate of hydrolysis is 4-(arylhydroxymethyl)-2-pyrazoline-5-one SOH.The second order rate constants of the reactions of S with hydroxidions and with 2-pyrazoline-5-ones P(-) are determined.The dependence of the hydrolytic decomposition of S on the pH value, substituents and temperature is suitable for the intermediate formation of SOH.