88696-72-4Relevant academic research and scientific papers
2-Amino-5,5-bis(hydroxymethyl)-1,3-thiazol-4(5H)-one and its spirodioxane compounds in the Mannich reaction
Ramsh,Ivanenko,Medvedskiy,Lagerev,Lazarev,Belobrzeckaja Costa
, p. 1086 - 1093 (2008/09/17)
It was found that the aminomethylation of 2-amino-5,5-bis(hydroxymethyl)-1, 3-thiazol-4(5H)-one and its spiro analogs using primary amines is accompanied by cyclization at the amidine fragment of the molecule with annelation of a tetrahydrotriazine ring.
INVESTIGATION OF THE REACTIVITIES AND TAUTOMERISM OF AZOLIDINES. 41. "ANOMALOUS" PRODUCTS OF AMINOMETHYLATION OF 2-IMINOTHIAZOLIDIN-4-ONE WITH AQUEOUS FORMALDEHYDE AND PRIMARY AMINES
Solov'eva, S. Yu.,Ramsh, S. M.,Ginak, A. I.
, p. 961 - 966 (2007/10/02)
The corresponding thiazolo-1,3,5-triazines, which are substituted in the C(7) position of the condensed heterocyclic system, are formed as a result of aminomethylation of 2-iminothiazolidin-4-one with aqueous formaldehyde and several pri
