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Acetamide, N-[(4-chlorophenyl)methyl]-2,2,2-trifluoro-, also known as a trifluoromethyl benzamide derivative, is a chemical compound with the molecular formula C10H8ClF3NO. It is widely utilized in pharmaceutical research and drug development due to its potential as an anticonvulsant and GABAA receptor modulator. Acetamide, N-[(4-chlorophenyl)methyl]-2,2,2-trifluorofunctions as a selective and potent GABA-receptor partial agonist, which makes it a significant tool for investigating the role of GABAergic neurotransmission in the central nervous system. It also holds promise as a therapeutic agent for treating various neurological disorders, although further research is necessary to elucidate its mechanism of action and clinical applications fully.

88708-69-4

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88708-69-4 Usage

Uses

Used in Pharmaceutical Research and Drug Development:
Acetamide, N-[(4-chlorophenyl)methyl]-2,2,2-trifluorois used as a research compound for its potential as an anticonvulsant and GABAA receptor modulator. Its role as a selective and potent GABA-receptor partial agonist aids in studying the GABAergic neurotransmission in the central nervous system.
Used in Neurological Disorders Treatment:
In the field of neurology, Acetamide, N-[(4-chlorophenyl)methyl]-2,2,2-trifluorois used as a potential therapeutic agent for the treatment of various neurological disorders. Its mechanism of action and clinical applications are under investigation to fully understand its efficacy and safety.
Used in Studying GABAergic Neurotransmission:
Acetamide, N-[(4-chlorophenyl)methyl]-2,2,2-trifluorois utilized in neuroscience research as a valuable tool for studying the role of GABAergic neurotransmission in the central nervous system, which is crucial for understanding the underlying mechanisms of several neurological conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 88708-69-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,7,0 and 8 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 88708-69:
(7*8)+(6*8)+(5*7)+(4*0)+(3*8)+(2*6)+(1*9)=184
184 % 10 = 4
So 88708-69-4 is a valid CAS Registry Number.

88708-69-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[(4-chlorophenyl)methyl]-2,2,2-trifluoroacetamide

1.2 Other means of identification

Product number -
Other names N-(p-chlorobenzyl)-2,2,2-trifluoroacetamide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:88708-69-4 SDS

88708-69-4Relevant academic research and scientific papers

Haloarenes in the Duff reaction under high pressures 2. Formylation and amidomethylation of haloarenes in trifluoroacetic acid

Sedishev, I. P.,Agafonov, N. E.,Kutin, A. A.,Zhulin, V. M.

, p. 2127 - 2130 (2007/10/03)

Reactions of haloarenes with urotropine in CF3COOH at elevated temperatures and high pressures give the corresponding aromatic aldehydes and/or N-(haloarylmethyl)trifluoroacetamides.The yields of the products and their ratio depend on electronic properties of substituents in the aromatic ring.The reaction carried out in a mixture of CF3COOH and (CF3CO)2O affords only amides. - Keywords: haloarenes; Duff reaction; high pressure; haloarenecarbaldehydes; N-(haloarylmethyl)trifluoroacetamides.

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