887130-01-0Relevant articles and documents
Applying lipase catalysis to access the enantiomers of dorzolamide intermediates
Turcu, Mihaela C.,Rantapaju, Maria,Kanerva, Liisa T.
experimental part, p. 5594 - 5600 (2010/03/01)
The kinetic resolution of three dorzolamide intermediates has been studied in the presence of Burkholderia cepacia li-pase in organic solvents. All the stereoisomers of 6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-4-ol were prepared starting from the ra