88722-94-5Relevant academic research and scientific papers
Perfluoroalkylsulfonyl fluoride in organic synthesis: a facile synthesis of 17α-hydroxy steroids
Guo, Peng-Peng,Ding, Kai
, p. 4096 - 4100 (2015/08/03)
Abstract A facile synthesis of 17α-hydroxy steroids with perfluoroalkylsulfonyl fluoride as hydroxyl activating agent was reported. The method features mild (40 °C), rapid (0.5 h), high yield, and high functional group tolerance. Notably, the method is applicable to HCOOH and CF3COOH, unusual and synthetically useful nucleophiles in hydroxyl inversion reaction.
Benzoyl Trifluoromethanesulfonate. A Mild Reagent for the Benzoylation of Sterically Hindered Hydroxyls
Brown, Lindsey,Koreeda, Masato
, p. 3875 - 3880 (2007/10/02)
Benzoyl trifluoromethanesulfonate (BzOTf) is a highly efficient reagent for the benzoylation of a variety of alcohols under mild conditions.These include hindered secondary and tertiary hydroxyls, phenols, and α-glycols.Sensitive functionality is stable when the reaction is performed in the presence of pyridine.Several unique rearrangements of Lewis acidsensitive compounds were also effected.
Benzoyl Trifluoromethanesulphonate. A Highly Efficient Benzoylating Agent for Sterically Hindered Hydroxyl Groups
Koreeda, Masado,Brown, Lindsey
, p. 1113 - 1115 (2007/10/02)
Reactions of benzoyl trifluoromethanesulphonate (BzOTf) with a variety of alcohols, including some with sterically hindered secondary and tertiary hydroxy groups, with phenolic compounds, and with 1,2-diols at low temperatures provide the corresponding benzoates in high yield.
