88722-94-5

Basic information

• Product Name: estradiol 3,17a-benzoate
• Synonyms: estradiol 3,17a-benzoate
• CAS NO: 88722-94-5
• Molecular Weight: 480.604
• Mol File: 88722-94-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: estradiol 3,17a-benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: estradiol 3,17a-benzoate(88722-94-5)
• EPA Substance Registry System: estradiol 3,17a-benzoate(88722-94-5)

Safety Data

• Hazardous Substances Data: 88722-94-5(Hazardous Substances Data)

Upstream product

• 50-50-0 Estradiol 3-benzoate 
• 65-85-0 benzoic acid 
• 98-88-4 benzoyl chloride 
• 36967-85-8 benzoyl triflate 
• 57-91-0 α-estradiol 

Relevant articles and documents

Perfluoroalkylsulfonyl fluoride in organic synthesis: a facile synthesis of 17α-hydroxy steroids

Abstract A facile synthesis of 17α-hydroxy steroids with perfluoroalkylsulfonyl fluoride as hydroxyl activating agent was reported. The method features mild (40 °C), rapid (0.5 h), high yield, and high functional group tolerance. Notably, the method is applicable to HCOOH and CF3COOH, unusual and synthetically useful nucleophiles in hydroxyl inversion reaction.

Benzoyl Trifluoromethanesulphonate. A Highly Efficient Benzoylating Agent for Sterically Hindered Hydroxyl Groups

Reactions of benzoyl trifluoromethanesulphonate (BzOTf) with a variety of alcohols, including some with sterically hindered secondary and tertiary hydroxy groups, with phenolic compounds, and with 1,2-diols at low temperatures provide the corresponding benzoates in high yield.