887331-19-3Relevant academic research and scientific papers
Metal-free catalytic nucleophilic substitution of propargylic alcohols
Sanz, Roberto,Martinez, Alberto,Alvarez-Gutierrez, Julia M.,Rodriguez, Felix
, p. 1383 - 1386 (2006)
Organic acids such as PTS efficiently catalyze direct nucleophilic substitutions of the hydroxy groups of propargylic alcohols with a large variety of carbon- and heteroatom-centered nucleophiles. Reactions can be conducted under mild conditions and in air without the need for dried solvents. Reactions on multigram scales are also possible. Wiley-VCH Verlag GmbH & Co. KGaA, 2006.
Synthesis of 1,5-enynes by Broonsted acid catalyzed substitution of propargylic alcohols and one-pot synthesis of bicyclo[3.1.0]hexenes
Sanz, Roberto,Martinez, Alberto,Miguel, Delia,Alvarez-Gutierrez, Julia M.,Rodriguez, Felix
, p. 3252 - 3256 (2008/09/16)
A practical air and moisture tolerant procedure for the preparation of 1,5-enynes from propargylic alcohols by the Bronsted acid catalyzed direct propargylic substitution of the hydroxy group with allylsilanes is described. Also, a straightforward sequent
