887475-71-0

Basic information

• Product Name: 6-BROMO-8-(METHYLTHIO)IMIDAZO[1,2-A]PYRAZINE
• Synonyms: 6-BROMO-8-(METHYLTHIO)IMIDAZO[1,2-A]PYRAZINE;6-Bromo-8-methylthioimidazo[1,2-a]pyrazinamine;6-Bromo-8-(methylthio)
• CAS NO: 887475-71-0
• Molecular Formula: C₇H₆BrN₃S
• Molecular Weight: 244.11
• Mol File: 887475-71-0.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Density: 1.81
• PKA: 1.46±0.30(Predicted)
• CAS DataBase Reference: 6-BROMO-8-(METHYLTHIO)IMIDAZO[1,2-A]PYRAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-BROMO-8-(METHYLTHIO)IMIDAZO[1,2-A]PYRAZINE(887475-71-0)
• EPA Substance Registry System: 6-BROMO-8-(METHYLTHIO)IMIDAZO[1,2-A]PYRAZINE(887475-71-0)

Safety Data

• Hazardous Substances Data: 887475-71-0(Hazardous Substances Data)

Usage

General Description

6-Bromo-8-(methylthio)imidazo[1,2-a]pyrazine is a chemical compound with the molecular formula C7H6BrN3S. It is a heterocyclic organic compound containing a five-membered imidazole ring fused to a six-membered pyrazine ring with a bromine atom at position 6 and a methylthio group at position 8. 6-Bromo-8-(methylthio)imidazo[1,2-a]pyrazine has potential applications in pharmaceutical research and drug development due to its diverse biological activities, including antimicrobial, antiviral, and anticancer properties. It is also used as a building block in the synthesis of various pharmacologically active molecules. Additionally, 6-Bromo-8-(methylthio)imidazo[1,2-a]pyrazine is a useful tool for studying structure-activity relationships and the mechanism of action of biologically active compounds.

Upstream product

• 1057261-12-7 6,8-dibromoimidazo[1,2-a]pyrazine hydrobromide 
• 5188-07-8 sodium thiomethoxide 
• 63744-22-9 6,8-dibromoimidazo[1,2-a]pyrazine 

Downstream Products

• 887475-73-2 C₁₇H₁₈N₄O₂S 
• 887475-72-1 C₁₇H₁₈N₄O₂S 
• 1263425-47-3 4-[6-bromo-8-(methylsulfonyl)imidazo[1,2-a]pyrazin-3-yl]-N-cyclopropylbenzamide 
• 1263421-51-7 4-(6-bromo-8-isobutylamino-imidazo[1,2-a]pyrazin-3-yl)-N-cyclopropyl-benzamide 
• 1263421-52-8 4-{6-(4-cyanophenyl)-8-[(2-methylpropyl)amino]imidazo[1,2-a]pyrazin-3-yl}-N-cyclopropylbenzamide 
• 1094070-46-8 C₈H₉N₃S 
• 1412909-13-7 6-(3-chlorophenyl)-8-(methylthio)-3-p-tolylimidazo[1,2-a]pyrazine 
• 1412909-15-9 8-(methylthio)-6-(3-nitrophenyl)-3-phenylimidazo[1,2-a]pyrazine 
• 1412909-14-8 ethyl 4-(8-(methylthio)-3-phenylimidazo[1,2-a]pyrazin-6-yl)benzoate 
• 1412909-12-6 3-(3,4-dimethylphenyl)-8-(methylthio)-6-(3-(trifluoromethyl)phenyl)imidazo[1,2-a]pyrazine 
• 1412909-16-0 6-(4-methoxyphenyl)-8-(methylthio)-3-phenylimidazo[1,2-a]pyrazine 
• 1412909-11-5 3-(3-methoxyphenyl)-8-(methylthio)-6-phenylimidazo[1,2-a]pyrazine 
• 1412909-19-3 3-(8-(4-methoxyphenyl)-6-phenylimidazo[1,2-a]pyrazin-3-yl)benzonitrile 
• 1412909-10-4 3-(8-(methylthio)-6-phenylimidazo[1,2-a]pyrazin-3-yl)benzonitrile 

Relevant articles and documents

SUBSTITUTED PENTA-FUSED HEXA-HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, DRUG COMBINATION AND USE THEREOF

A type of substituted penta-fused hexa-heterocyclic compounds having selective inhibition for PIKfyve kinase, a pharmaceutically acceptable salt and pharmaceutically acceptable solvate thereof, a method for the preparation thereof, a pharmaceutical composition comprising the same, and use of these compounds in the manufacture of a medicament for preventing or treating a disease associated with PIKfyve in vivo, in particular in the manufacture of a medicament for preventing or treating tumor growth and metastasis.

6-THIO-SUBSTITUTED IMIDAZOPYRAZINES FOR USE AS MPS-1 AND TKK INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS

The present invention relates to substituted imidazopyrazine compounds of general formula (I): (I) in which R1, R2, R3, R4 and R5 are as defined in the claims, to methods of and intermediates for prep

6-THIO-SUBSTITUTED IMIDAZOPYRAZINES FOR USE AS MPS-1 AND TKK INHIBITORS IN THE TREATMENT OF HYPERPROLIFERATIVE DISORDERS

The present invention relates to substituted imidazopyrazine compounds of general formula (I) : (I) in which R1, R2, R3, R4 and R5 are as defined in the claims, to methods of and intermediates for pre