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N-(Ethoxycarbonyl)ethyl-4-fluoroaniline is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

887574-32-5

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887574-32-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 887574-32-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,7,5,7 and 4 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 887574-32:
(8*8)+(7*8)+(6*7)+(5*5)+(4*7)+(3*4)+(2*3)+(1*2)=235
235 % 10 = 5
So 887574-32-5 is a valid CAS Registry Number.

887574-32-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 3-(4-fluoroanilino)propanoate

1.2 Other means of identification

Product number -
Other names PC6097

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:887574-32-5 SDS

887574-32-5Downstream Products

887574-32-5Relevant articles and documents

Preparation method of 3-(phenyl amino)ethyl propionate type compound

-

Paragraph 0019, (2018/09/29)

The invention belongs to the technical field of chemical synthesis and particularly relates to a preparation method of a 3-(phenyl amino)ethyl propionate type compound. The method is realized throughthe following steps: mixing an aromatic amine compound w

Heterocyclic Compounds and Methods of Use

-

Paragraph 0777; 0778, (2018/03/10)

This disclosure provides compounds and methods of using those compounds to treat metabolic disorders and hyperproliferative disorders, including administration of the compounds in conjunction with hormone receptor antagonists.

Arylamino containing hydroxamic acids as potent urease inhibitors for the treatment of Helicobacter pylori infection

Liu, Qi,Shi, Wei-Kang,Ren, Shen-Zhen,Ni, Wei-Wei,Li, Wei-Yi,Chen, Hui-Min,Liu, Pei,Yuan, Jing,He, Xiao-Su,Liu, Jia-Jia,Cao, Peng,Yang, Pu-Zhen,Xiao, Zhu-Ping,Zhu, Hai-Liang

, p. 126 - 136 (2018/07/13)

A novel series of aniline-containing hydroxamic acids were designed, synthesized and evaluated as anti-virulence agents for the treatment of gastritis and gastric ulcer caused by Helicobacter pylori. In vitro enzyme-based screen together with in vivo assays and structure?activity relationship (SAR) studies led to the discovery of three potent urease inhibitors 3-(3,5-dichlorophenylamino)–N-hydroxypropanamide (3a), 3-(2-chlorophenylamino)–N-hydroxypropanamide (3d) and 3-(2,4-dichlorophenylamino)–N-hydroxypropanamide (3n). Compounds 3a, 3d and 3n showed excellent urease inhibition with IC50 values 0.043 ± 0.005, 0.055 ± 0.008 and 0.018 ± 0.002 μM, and significantly depressed gastritis developing at the dose of 32 mg/kg b. i.d with eradication rates of H. pylori reaching 92.3, 84.6 and 100%, respectively. Preliminary safety studies (acute toxicity in mice) disclosed that 3a, 3d and 3n was well-tolerated in KM mice with LD50s of 2982.8, 3349.4 and 3126.9 mg/kg, respectively. Collectively, the data obtained in this study indicate that 3a, 3d and 3n, in particular 3n, could considered as promising candidates for the potential treatment of H. pylori caused gastritis and gastric ulcer, and hence merit further studies.

A fluorine-containing agents compound and its preparation method and application (by machine translation)

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Paragraph 0057; 0059; 0060, (2018/08/28)

The present invention provides a fluorine-containing agents compound and its preparation method and application, the fluorine-containing agents compounds have the formula I illustrated structure, its structure is simple, has good anticoagulant activity, c

A fluorine-containing agents compound and its preparation method and application (by machine translation)

-

Paragraph 0050; 0052; 0053, (2018/08/28)

The present invention provides a fluorine-containing agents compound and its preparation method and application, the fluorine-containing agents compounds have the formula I illustrated structure, its structure is simple, has good anticoagulant activity, c

Fluorine-containing benzimidazole compound and preparation method thereof and application thereof

-

Paragraph 0081; 0083; 0084, (2018/11/22)

The present invention provides a fluorine-containing benzimidazole compound and a preparation method thereof and an application thereof. The fluorine-containing benzimidazole compound has a structureas shown in a formula I, is simple in structure, has goo

Fluorine-containing benzimidazole compounds and preparation method and application thereof

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Paragraph 0088; 0090; 0091, (2018/11/22)

The invention provides fluorine-containing benzimidazole compounds and a preparation method and application thereof. The fluorine-containing benzimidazole compounds have a structure represented in a formula I; the fluorine-containing benzimidazole compoun

Design, synthesis, and anti-thrombotic evaluation of some novel fluorinated thrombin inhibitor derivatives

Chen, Haifeng,Ren, Yujie

, p. 408 - 420 (2015/06/08)

Computer-aided simulation was used to design and synthesize nine novel fluorinated thrombin inhibitor derivatives. These compounds were confirmed by spectral analyses (1H NMR, 13C NMR, and FT-ICR-MS). Their inhibitory activities agai

BICYCLIC THIAZOLES AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS

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Page/Page column 15, (2012/10/08)

The present invention relates to novel bicyclic thiazoles which are positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (“mGluR5”) and which are useful for the treatment or prevention of disorders associated with glutamate dysfunction and diseases in which the mGluR5 subtype of receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which mGluR5 is involved.

BICYCLIC THIAZOLES AS ALLOSTERIC MODULATORS OF MGLUR5 RECEPTORS

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Page/Page column 44-45, (2011/07/07)

The present invention relates to novel bicyclic thiazoles of formula (I) which are positive allosteric modulators of the metabotropic glutamate receptor subtype 5 ("mGluR5") and which are useful for the treatment or prevention of disorders associated with glutamate dysfunction and diseases in which the mGluR5 subtype of receptors is involved. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which mGluR5 is involved.

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