887642-11-7

Upstream product

• 65715-04-0 (E)-2-Oxo-4-phenyl-but-3-enoyl chloride 
• 100-51-6 benzyl alcohol 
• 1914-59-6 (E)-2-oxo-4-phenyl-3-butenoic acid 
• 35249-73-1 benzyl chlorooxalate 
• 30094-01-0 (E)-(2-phenylethenyl)magnesium bromide 

Downstream Products

• 1042740-75-9 benzyl 2-(4-fluorophenyl)-2-hydroxy-4-phenylbut-3-enoate 
• 1042740-81-7 benzyl 2-hydroxy-2-(3-methoxyphenyl)-4-phenylbut-3-enoate 
• 1042740-79-3 benzyl 2-hydroxy-2-(3-methylphenyl)-4-phenylbut-3-enoate 
• 1042740-71-5 benzyl 2-hydroxy-2-(4-methylphenyl)-4-phenylbut-3-enoate 
• 1042740-85-1 benzyl 2-hydroxy-2-(naphthalen-2-yl)-4-phenylbut-3-enoate 
• 1042740-73-7 benzyl (2S,3E)-2-hydroxy-2-(4-methoxyphenyl)-4-phenylbut-3-enoate 
• 1042740-77-1 benzyl 2-(4-trifluoromethylphenyl)-2-hydroxy-4-phenylbut-3-enoate 
• 1042740-69-1 benzyl 2-hydroxy-2-phenyl-4-phenylbut-3-enoate 
• 1595074-89-7 benzyl (E)-2-[ethyl(4-methoxyphenyl)amino]-4-phenylbut-3-enoate 
• 1615654-95-9 benzyl (2S,E)-4-oxo-2-styryl-3,4-dihydro-2H-pyran-2-carboxylate 

Relevant academic research and scientific papers

Tandem N -alkylation/vinylogous aldol reaction of β,γ-Alkenyl α-iminoester

This report describes a highly regioselective tandem N-alkylation/ vinylogous aldol reaction of β,γ-alkenyl α-iminoesters. The sulfur group improves the regioselectivity of the directed vinylogous aldol reaction, providing a new synthetic method of 3-amino-2-pyrones.

Enantioselective rhodium-catalyzed addition of arylboronic acids to α-ketoesters

(Chemical Figure Presented) Rhodium catalysis: The first example of a catalytic asymmetric addition of arylboronic acids to α-ketoesters was realized by using a chiral RhI-spirophosphite ligand complex in aqueous solvent to provide tertiary α-hydroxyesters in good yields with high enantioselectivities (see scheme; DCE = 1,2-dichloroethane).