887771-98-4

Usage

Uses

Used in Pharmaceutical Industry:
(4R,4AS,8AS)-4-(4-METHOXYPHENYL)OCTAHYDRO-2H-PYRANO[2,3-D]PYRIMIDIN-2-ONE is used as a potential pharmaceutical candidate for [application reason] due to its heterocyclic structure and potential pharmacological properties.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (4R,4AS,8AS)-4-(4-METHOXYPHENYL)OCTAHYDRO-2H-PYRANO[2,3-D]PYRIMIDIN-2-ONE is used as a subject of study for [application reason] because of its unique chemical structure and the possibility of discovering new therapeutic applications through further research and testing.

Upstream product

• 110-87-2 3,4-dihydro-2H-pyran 
• 123-11-5 4-methoxy-benzaldehyde 
• 57-13-6 urea 

Relevant academic research and scientific papers

An efficient one-pot three-component synthesis of 4-phenyl hexahydro-1H-pyrano[2,3-d]pyrimidin-2(8aH)-one derivatives

(Chemical Equation Presented) An efficient method for the synthesis of a series of 4-phenylhexahydro-1H-pyrano[2,3-d]pyrimidin-2(8aH)-one derivatives via the one-pot three-component reaction of aromatic aldehydes, urea or thiourea and 3,4-dihydro-2H-pyran

Antimony trichloride catalyzed three-component reaction of urea, aldehydes and cyclic enol ethers: A novel route to 4-arylhexahydrofuro[2,3-d]pyrimidin- 2(3H)-ones

Antimony trichloride efficiently catalyses diastereoselective three-component reaction of urea, aromatic aldehydes and 2,3-dihydrofuran or 3,4-dihydro-2H-pyran leading to 4-arylhexahydrofuro[2,3-d]pyrimidin-2(3H)-ones and 4-arylhexahydro-1H-pyrano[2,3-d]p

Two novel diastereoselective three-component reactions of alkenes or 3,4-dihydro-(2H)-pyran with urea/thiourea-aldehyde mixtures: [4 + 2] cycloaddition vs Biginelli-type reaction

Two novel diastereoselective three-component reactions of alkenes or 3,4-dihydro-(2H)-pyran with urea/thiourea-aldehyde mixtures are described.

Ionic liquid-catalyzed one-pot synthesis of 1 H-pyrano[2,3-d[pyrimidin-2(8a H)-one derivatives via three-component reaction under solvent-free conditions

A series of 1H-pyrano[2,3-d]pyrimidin-2(8aH)-one derivatives were synthesized via one-pot, three-component reaction of aromatic aldehydes, urea or thiourea, and 3,4-dihydro-2H-pyran using the green and inexpensive Brnsted acidic ionic liquid 1-methyl-2-py