88783-79-3Relevant academic research and scientific papers
SMALL MOLECULE COMPOUNDS FOR STEM CELL DIFFERENTIATION
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Page/Page column 70; 71, (2010/04/25)
Methods and small molecule compounds for stem cell differentiation are provided. One example of a class of compounds that may be used is represented by the compound having the structure IA or IB in the form of free base or a pharmaceutically acceptable salt, hydrate, solvate or N-oxide thereof. R1 is independently hydrogen or (C1-C6)alkyl; R2 is independently hydrogen, (C1-C6)alkyl, aryl, or heteroaryl; R2' is independently hydrogen, (C1-C6)alkyl, CF3 or C2F5; R3 is independently (C1-C6)alkyl, aryl, 2-tetrahydrofuryhnethyl, an aliphatic tertiary amine, or 4-methoxybenzyl; or R2 and R3 may be joined together to form a 5 or 6 member ring lactone; R4 is independently hydrogen, (C1-C6)alkyl, a 2- or 4-R5-substituted aromatic ring selected from a 4-R5-phenyl or a 2-R5-5-pyridyl, aryl, heteroaryl, aliphatic tertiary amine or halogen; and R5, R5', R6, R6', R7, R7' are each independently hydrogen, (C1-C6)alkyl, aryl, optionally substituted phenyl, heteroaryl, a heterocyclic ring, an aliphatic tertiary amine, or halogen.
ELECTROCHEMISTRY OF SELF-COMPLEXATION. I. ELECTROCHEMISTRY OF PICRYL SERIES SELF-COMPLEXATION
Bumin, K. P.,Il'ina, I. G.,Moiseeva, A. A.,Reutov, O. A.
, p. 155 - 159 (2007/10/02)
The contribution of self-complexed molecular fragments to the total imtramolecular contact charge transfer between fragments of self-complexed molecules ("contact transfer") was studied by the electrochemical behavior of picryl series compounds and their mono- and dinitro analogs as well as the amines used in their synthesis.In contrast to reduction potentials the self-complexing oxidation potentials were highly dependent on the type of donor fragment.Based on a comparisonof the oxidation potentials of compounds of the trinitrophenyl and dinitrophenyl series containing the same donor fragment we proposed a formula for evaluating the contribution of the contact charge transfer to direct bonding, according to which it was no more than 10percent.
FREE-RADICAL HYDROXYMETHYLATION OF BENZIMIDAZOLE
Khristich, B.I.,Tsupak, E.B.,Kononogova, O.I.
, p. 1299 - 1302 (2007/10/02)
Several benzimidazole derivatives were subjected to free-radical hydroxymethylation.Benzimidazole displays lower activity than quinoline in the first stage of the transformation, viz., in the addition of the hydroxymethyl radical.The yields of hydroxymeth
