88784-37-6

Usage

Uses

Used in Pharmaceutical Industry:
(S)-3-(3-METHOXYPHENYL)PIPERIDINE is used as a central nervous system targeting agent for its potential pharmacological properties. It may contribute to the development of drugs that address neurological disorders and conditions.
Used in Chemical Synthesis:
(S)-3-(3-METHOXYPHENYL)PIPERIDINE serves as a building block in the synthesis of various organic molecules, facilitating the creation of new compounds with diverse applications across different industries.

InChI:InChI=1/C12H17NO/c1-14-12-6-2-4-10(8-12)11-5-3-7-13-9-11/h2,4,6,8,11,13H,3,5,7,9H2,1H3/t11-/m1/s1

Upstream product

• 1234836-16-8 3-(3-methoxyphenyl)-1-p-toluenesulfonylpiperidine 
• 79601-21-1 3-(3-methoxyphenylpiperidine) 
• 2398-37-0 3-methoxyphenyl bromide 
• 885693-20-9 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester 
• 3105-95-1 pipecolinic acid 
• 61364-70-3 1-(3-bromoprop-1-en-2-yl)-3-methoxybenzene 
• 1234835-76-7 N-(but-3-enyl)-N-(2-(3-methoxyphenyl)allyl)-p-toluenesulfonamide 
• 1234835-96-1 5-(3-methoxyphenyl)-1-p-toluenesulfonyl-1,2,3,6-tetrahydropyridine 
• 89874-44-2 N-benzyl-3(S)-(3-methoxyphenyl)piperidine 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 4373-67-5 3-(3-methoxyphenyl)pyridine 
• 626-55-1 3-Bromopyridine 
• 450416-68-9 (3S)-1-[(1S)-2-hydroxy-1-phenylethyl]-3-(3-methoxyphenyl)piperidine 
• 450416-64-5 (3S,8S,8aS)-8-(3-methoxyphenyl)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 

Downstream Products

• 89874-51-1 (+)-(S)-3-(3-methoxyphenyl)-1-propylpiperidine 
• 147161-52-2 (S)-N-cyanomethyl-3-(3-methoxyphenyl)piperidine 
• 89874-67-9 S-3-(3-Methoxyphenyl-N-ethyl)piperidine 
• 85966-89-8 preclamol 
• 146798-88-1 S-(-)-3-<(3-(((trifluoromethyl)sulfonyl)oxy)phenyl)-N-n-propyl>piperidine 
• 1071930-35-2 trifluoromethanesulfonic acid 3-((S)-1-propyl-1-oxo-piperidin-3-yl)-phenyl ester 
• 1602922-49-5 (4-chlorophenyl)-carbamic acid (S)-2,2,2-trifluoro-1-[(S)-3-(3-methoxyphenyl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride 
• 147161-63-5 (S)-N-propyl-3-(3-methoxy-4-nitrophenyl)piperidine 
• 147161-65-7 (S)-N-propyl-3-(3-methoxy-4-aminophenyl)piperidine 

Relevant academic research and scientific papers

TRIAZACYCLODODECANSULFONAMIDE ("TCD")-BASED PROTEIN SECRETION INHIBITORS

Provided herein are triazacyclododecansulfonamide ("TCD")-based protein secretion inhibitors, such as inhibitors of Sec61, methods for their preparation, related pharmaceutical compositions, and methods for using the same. For example, provided herein are compounds of Formula (I) and pharmaceutically acceptable salts and compositions including the same. The compounds disclosed herein may be used, for example, in the treatment of diseases including inflammation and/or cancer.

Stereoselective synthesis of (?)-3-PPP through palladium-catalysed unactivated C(sp3)–H arylation at the C-3 position of L-pipecolinic acid

An efficient route for the preparation of (?)-3-PPP(preclamol) using the highly stereoselective palladium-catalysed C(sp3)-H arylation and radical decarboxylation reaction as the key steps is described. The chiral center at the C-3 position of

Enantioselective synthesis of 2-substituted and 3-substituted piperidines through a bromoaminocyclization process

A catalytic enantioselective bromocyclization of olefinic amides using amino-thiocarbamates as the catalysts has been developed. The resulting enantioenriched 2-substituted 3-bromopiperidines can readily be transformed to 3-substituted piperidines through

Highly flexible synthesis of chiral azacycles via iridium-catalyzed hydrogenation

A range of saturated chiral azacycles has been prepared in high yield and with high selectivity from simple starting materials. A modular approach with ring-closing metathesis as a key step was used to produce a number of five-, six-, and seven-membered c

N-OXIDE AND/OR DI-N-OXIDE DERIVATIVES OF DOPAMINE RECEPTOR STABILIZERS/MODULATORS DISPLAYING IMPROVED CARDIOVASCULAR SIDE-EFFECTS PROFILES

The invention relates to N-oxide and/or di-N-oxide derivatives of dopamine receptor stabilizers/modulators having the general formula (1) or (2) and pharmaceutical preparations containing the said compounds. Further, the invention relates the use of the s

Dynamic kinetic resolution of racemic γ-aryl-δ-oxoesters. Enantioselective synthesis of 3-arylpiperidines

Cyclodehydration of racemic γ-aryl-δ-oxoesters with (R)- or (S)-phenylglycinol stereoselectively affords bicyclic δ-lactams, in a process that involves a dynamic kinetic resolution. Subsequent reduction of these lactams leads to enantiopure 3-arylpiperidines. Starting from racemic aldehyde esters, this short sequence has been applied to the synthesis of (R)-3-phenylpiperidine and the antipsychotic drug (-)-3-PPP (an (S)-3-arylpiperidine), whereas starting from racemic ketone esters enantiopure cis-2-alkyl-3-arylpiperidines are prepared.

CHIRAL, POTENTIALLY IRREVERSIBLE LIGANDS FOR THE SIGMA RECEPTOR BASED ON THE STRUCTURE OF 3-(3-HYDROXYPHENYL)-N-PROPYLPIPERIDINE (3-PPP)

(+)-3-PPP is an optically active, highly potent and selective ligand for sigma receptors.The resolved enantiomeric pairs of potential irreversible sigma ligands (5a,b) and (9a,b) were designed and synthesized based on the structure of 3-PPP.An improved me

1,3-disubstituted piperidine compounds as neuroleptic agents

Certain novel 1-(substituted-alkyl)-3-(3-hydroxyphenyl)piperidine compounds, and the pharmaceutically-acceptable acid-addition salts thereof, possess pharmaceutical activity as neuroleptic agents, and they are useful for treating psychotic disorders, e.g.

Resolved 3-(3-Hydroxyphenyl)-N-n-propylpiperidine and Its Analogues: Central Dopamine Receptor Activity

Seven enantiomeric pairs of N-alkyl analogues of 3-(3-hydroxyphenyl)-N-n-propylpiperidine (3-PPP, 12) have been synthesized and evaluated pharmacologically (biochemistry and behavior) in order to examine their ability to interact with central dopamine (DA