888474-32-6

Upstream product

• 6048-29-9 triphenylphenacylphosphonium bromide 
• 4998-15-6 4-chlorophenylglyoxal 
• 119492-84-1 2-phenyl-5-(p-chlorophenyl)furan 
• 110029-70-4 (4-chloro-phenacyl)-dimethyl-phenacyl-ammonium; bromide 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 107487-79-6 trans-1-(4-Chlorophenyl)-4-phenylbut-2-ene-1,4-dione 

Relevant academic research and scientific papers

Oxidative ring opening of 1,3-diarylbenzo[c]heterocycles using m-CPBA: Preparation of 1,2-diaroylbenzenes

An unprecedented oxidative cleavage of benzo[c]heterocycles using m-CPBA is reported. The reaction of 1,3-diaryl benzo[c]heterocycles with m-CPBA (meta-chloroperoxybenzoic acid) at room temperature for 5 min led to the formation of 1,2-diaroylbenzenes in good to excellent yields.

Development of the Julia asymmetric epoxidation reaction. Part 2. Application of the oxidation to alkyl enones, enediones and unsaturated keto esters

Polyleucine-based systems have been used to catalyse the asymmetric oxidation of a variety of alkyl enones 1-4, 9-14, an enynone 16 and a dienone 17 to afford the corresponding epoxides 5-8, 18-26 in good to excellent yield and optical purity. A range of enediones 30-32, 34 and one unsaturated keto ester 33 have also been epoxidised stereoselectively to afford optically active epoxides 35-39. The epoxidations were carried out with basic peroxide as the oxidant; the polyleucine catalyst was prepared from leucine N-carboxyanhydride using 1,3-diaminopropane, water (employing a humidity cabinet) or a polystyrene immobilised amine as the initiator. Preliminary mass spectral data on material derived from L-leucine and 1,3-diaminopropane (DAP-PLL) suggest that the catalyst consists of material that contains 22 ± 10 leucine residues.