88884-37-1Relevant academic research and scientific papers
A Versatile Synthesis of Functionalised 2-Aminoquinolines by Mercury Controlled Cyclisation of 2-Vinylphenylthioureas
Wiggall, Kenneth J.,Richardson, Stewart K.
, p. 867 - 870 (2007/10/02)
4-(4-Hydroxyphenyl)-2-phenylamino-1,8-naphthyridine was prepared via cyclization of N-phenyl-N'-3-(4-hydroxyphenethen-1-yl)pyridin-2-ylthiourea in the presence of mercuric oxide.Derivatives of 4-methyl-2-aminoquinolines were prepared in a similar manner f
Improved Procedures for the Preparation of Cycloalkyl-, Arylalkyl-, and Arylthioureas
Rasmussen, C. R.,Villani, F. J.,Weaner, L. E.,Reynolds, B. E.,Hood, A. R.,et al.
, p. 456 - 459 (2007/10/02)
An improved procedure for the preparation of arylthioureas consists of the reaction of benzoyl isothiocyanate with anilines in acetone and debenzoylation of the resultant N-aryl-N'-benzoylthioureas with 5percent aqueous sodium hydroxide.Bicycloalkylthioureas and N-(arylalkyl)thioureas (e.g. 9H-9-fluorenylthiourea) are directly prepared from the corresponding isothiocyanates and ammonia.
