889099-13-2Relevant academic research and scientific papers
Searching for cyclin-dependent kinase inhibitors using a new variant of the cope elimination
Griffin, Roger J.,Henderson, Andrew,Curtin, Nicola J.,Echalier, Aude,Endicott, Jane A.,Hardcastle, Ian R.,Newell, David R.,Noble, Martin E. M.,Wang, Lan-Zhen,Golding, Bernard T.
, p. 6012 - 6013 (2007/10/03)
β-Piperidinoethylsulfides are oxidized by m-chloroperbenzoic acid to intermediates containing both N-oxide and sulfone functions. These undergo a Cope-type elimination to a vinylsulfone that can be captured by amines to afford β-aminoethylsulfones. When a
