889099-60-9

Upstream product

• 889099-45-0 3-(1-p-Tolyl-vinyl)-1,2,5-trioxa-spiro[5.5]undecan-9-one 
• 132533-10-9 2-Hydroperoxy-3-p-tolyl-but-3-en-1-ol 
• 130633-06-6 (E)-3-(4-methylphenyl)-but-2-en-1-ol 

Relevant academic research and scientific papers

Orally active 1,2,4-trioxanes: Synthesis and antimalarial assessment of a new series of 9-functionalized 3-(1-arylvinyl)-1,2,5-trioxaspiro[5.5]undecanes against multi-drug-resistant Plasmodium yoelii nigeriensis in mice

Using easily accessible keto-trioxanes 7a-g as the starting materials, a series of new variously functionalized 1,2,4-trioxanes 10-36 have been prepared and evaluated for antimalarial activity against multi-drug-resistant Plasmodium yoelii nigeriensis in