88910-22-9

Basic information

• Product Name: 2-Furanmethanol, 5-(aminomethyl)-
• CAS NO: 88910-22-9
• Molecular Formula: C6H9NO2
• Molecular Weight: 127.143
• Mol File: 88910-22-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Furanmethanol, 5-(aminomethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Furanmethanol, 5-(aminomethyl)-(88910-22-9)
• EPA Substance Registry System: 2-Furanmethanol, 5-(aminomethyl)-(88910-22-9)

Safety Data

• Hazardous Substances Data: 88910-22-9(Hazardous Substances Data)

Usage

General Description

2-Furanmethanol, 5-(aminomethyl)- is a chemical compound with the molecular formula C6H7NO2. It is a derivative of 2-furanmethanol, a heterocyclic organic compound. The presence of the aminomethyl group in this compound makes it potentially useful in organic synthesis, especially in the production of pharmaceuticals and agrochemicals. It also has potential applications in the field of materials science, due to its ability to form complexes with various metals and its potential catalytic properties. Additionally, it can be used as a building block in the synthesis of other organic compounds with specific functional properties. Overall, 2-Furanmethanol, 5-(aminomethyl)- has versatile potential applications in various fields, making it a compound of interest for further research and development.

Upstream product

• 67-47-0 5-hydroxymethyl-2-furfuraldehyde 

Downstream Products

• 1121-78-4 5-Hydroxy-2-methylpyridine 
• 97-99-4 Tetrahydrofurfuryl alcohol 
• 617-89-0 furan-2-ylmethanamine 
• 98-00-0 (2-furyl)methyl alcohol 
• 18240-50-1 bis((furan-2-yl)methyl)amine 
• 2213-51-6 (furan-2,5-diyl) dimethanamine 
• 4048-33-3 6-amino-1-hexanol 

Relevant articles and documents

Reductive Amination, Hydrogenation and Hydrodeoxygenation of 5-Hydroxymethylfurfural using Silica-supported Cobalt- Nanoparticles

Efficient and selective conversion of renewable feedstocks to essential chemicals and fuels applying green and sustainable catalytic processes is of central importance and attracts scientific interest. Among different biomass-based feedstocks, 5-hydroxymethylfurfural (HMF) represents valuable platform compound widely used for the synthesis of valuable chemicals, fuels, and polymers. Here we report cobalt nanoparticles catalyzed reductive amination, hydrogenation and hydrodeoxygenation of HMF to produce furan based primary, secondary and tertiary amines including N-methylamines as well as 2,5-bis(hydroxymethyl)furan, (5-methylfuran-2-yl)methanol and selected N-, O-, and S-containing heterocycles. Key to success for this HMF valorization is the use of reusable silica supported cobalt-based nanoparticles, which have been prepared by the immobilization and pyrolysis of Co-terephthalic acid-piperazine MOF template on silica.

Reductive amination of furfural to furfurylamine using aqueous ammonia solution and molecular hydrogen: An environmentally friendly approach

A simple and highly efficient method was developed for the transformation of furfural (a biomass derived aldehyde) to furfurylamine by reductive amination using an aqueous solution of ammonia and molecular hydrogen as an amine source and a reducing agent, respectively. By choosing a suitable catalyst, such as Rh/Al2O3, and reaction conditions, a very high selectivity of furfurylamine (～92%) can be achieved within the reaction time of 2 h at 80 °C. A detailed analysis of the reaction system sheds some light on the reaction pathway and provides an understanding about each elementary step. The reaction was believed to proceed via an imine pathway although no such intermediate was detected because of the highly reactive nature. Optimization of different reaction parameters such as hydrogen pressure, temperature and substrate/ammonia mole ratio is shown to be critical to achieve high selectivity of furfurylamine. Time-dependent reaction profiles suggested that a Schiff base type intermediate was in the detectable range, which offers indirect evidence of the formation of imine. Competitive hydrogenation and amination of an aldehyde group were strongly dictated by the nature of the metal used. The studied protocol represents an environmentally benign process for amine synthesis, which can be effectively extended to the other aldehydes also. The studied catalyst could be recycled successfully without any significant loss of catalytic activity.