889654-06-2

Usage

Uses

Used in Organic Synthesis:
3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is used as a building block in organic synthesis for its ability to facilitate the creation of complex molecular structures. Its reactivity and stability make it a valuable component in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Chemical Research:
In the field of chemical research, 3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is employed as a reagent to explore its potential applications and reactions. Its unique properties allow researchers to investigate new pathways and mechanisms in chemical reactions, contributing to the advancement of scientific knowledge.
Used in Pharmaceutical Industry:
3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is used as a key intermediate in the development of pharmaceutical compounds. Its versatility in organic synthesis enables the creation of new drug candidates with potential therapeutic applications.
Used in Agrochemical Industry:
In agrochemicals, 3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is utilized as a precursor in the synthesis of pesticides and other agrochemical products. Its role in creating effective and stable compounds contributes to the development of solutions for crop protection and enhancement of agricultural productivity.
Used in Materials Science:
3-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate is also used in materials science for the development of new materials with specific properties. Its incorporation into the molecular structure of these materials can lead to advancements in areas such as polymers, coatings, and advanced materials with tailored characteristics for various applications.

Upstream product

• 916343-75-4 methyl 3-methoxy-5-(trifluoromethanesulfonyloxy)benzoate 
• 73183-34-3 bis(pinacol)diborane 
• 5368-81-0 methyl 3-methoxybenzoate 
• 56709-70-7 3-bromo-5-methoxy-benzoic acid methyl ester 
• 140472-69-1 3-bromo-5-hydroxy-benzoic acid 
• 19520-74-2 3-hydroxy-5-methoxy-benzoic acid methyl ester 

Downstream Products

• 1048330-11-5 [3-methoxy-5-(methoxycarbonyl)phenyl]boronic acid 
• 23523-94-6 1-methoxy-3-methoxycarbonyl-9H-carbazole 
• 4532-33-6 1-methoxy-3-methylcarbazole 
• 723-97-7 murrayanine 
• 3889-89-2 mukoeic acid 
• 603124-21-6 3-[((7S)-7-{[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-5,6,7,8-tetrahydro-2-naphthalenyl)oxy]-5-methoxybenzoic acid hydrochloride 
• 603123-21-3 C₃₂H₃₆ClNO₇ 

Relevant academic research and scientific papers

Synthesis of diverse 3-azido-5-(azidomethyl)benzene derivatives via formal C-H azidation and functional group-selective transformations

3-Azido-5-(azidomethyl)benzene derivatives are useful compounds for preparing diverse bistriazole compounds and photoaffinity probes for target identification of bioactive compounds. To more easily synthesize a diverse range of diazido compounds, a facile

Total synthesis of carbazole alkaloids

A Suzuki-Miyaura cross coupling, followed by triphenylphosphine mediated Cadogan reductive cyclization sequence provided efficient access to a series of carbazole alkaloids. In the present work, this approach was applied to the total synthesis of mukonine, clauszoline K, koenoline, murrayanine, murrayafoline A, mukoeic acid, glycoborine, glycozolicine, mukolidine, mukoline, glycozoline, 3-methoxy-9H-carbazole-1-carboxylic acid methyl ester, (3-methoxy-9H-carbazol-1-yl)-methanol, 3-methoxy-9H-carbazole-1-carbaldehyde, 3-methoxy-9H-carbazole-1-carboxylic acid, 2-methyl-9H-carbazole and nonsteroidal anti-inflammatory drug (NSAID) carprofen and its derivatives.

NOVEL TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS

The present invention is directed to tricyclic compounds, pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

TRICYCLIC COMPOUNDS AS ANTICANCER AGENTS

The present invention is directed to tricyclic compounds (I), pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

Targeting the heat shock protein 90 dimer with dimeric inhibitors

The design, synthesis, and biological evaluation of conformationally constrained coumermycin A1 analogues are reported. Compounds were evaluated against both breast cancer (SKBr3 and MCF7) and prostate cancer (PC3 mm2, A549, and HT29) cell lines. Non-noviosylated coumermycin A1 analogues that manifest potent antiproliferative activity resulting from Hsp90 inhibition are provided, wherein replacement of the stereochemically complex noviose sugar with readily available piperidine rings resulted in ü100 fold increase in antiproliferative activities as compared to coumermycin A1, producing small molecule Hsp90 inhibitors that exhibit nanomolar activities.

Discovery of a novel series of benzoic acid derivatives as potent and selective human β3 adrenergic receptor agonists with good oral bioavailability. 3. Phenylethanolaminotetraline (PEAT) skeleton containing biphenyl or biphenyl ether moiety

We designed a series of benzoic acid derivatives containing the biphenyl ether or biphenyl template on the RHS and a phenylethanolaminotetraline (PEAT) skeleton, which was prepared by highly stereoselective synthesis, to generate two structurally different lead compounds (10c, 10m) with a good balance of potency, selectivity, and pharmacokinetic profile. Further optimization of the two lead compounds to improve potency led to several potential candidates (i.e., 11f, 11l, 11o, 12b). In particular, biphenyl analogue 12b exhibited an excellent balance of high potency (EC50 = 0.38 nM) for β3, high selectivity over β1 and β2, and good pharmacokinetic properties in rats, dogs, and monkeys.