889939-79-1 Usage
Uses
Used in Pharmaceutical Research:
1-[4-(4-FLUOROPHENYL)TETRAHYDRO-2H-PYRAN-4-YL]METHANAMINE is used as a building block for the synthesis of new drug candidates due to its unique chemical structure and potential biological activity.
Used in Analytical Testing:
1-[4-(4-FLUOROPHENYL)TETRAHYDRO-2H-PYRAN-4-YL]METHANAMINE is used as a reference standard in analytical testing to ensure the accuracy and reliability of experimental results.
Used in Drug Development:
1-[4-(4-FLUOROPHENYL)TETRAHYDRO-2H-PYRAN-4-YL]METHANAMINE is used in drug development for its potential therapeutic uses, which may include the treatment of various diseases and conditions. Its pharmacological effects are of significant interest to researchers in the pharmaceutical industry.
Used in Chemical Synthesis:
1-[4-(4-FLUOROPHENYL)TETRAHYDRO-2H-PYRAN-4-YL]METHANAMINE is used in chemical synthesis to create new compounds with potential applications in various fields, such as materials science, agrochemicals, and specialty chemicals. Its unique structure allows for the development of novel molecules with specific properties and functions.
Check Digit Verification of cas no
The CAS Registry Mumber 889939-79-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,9,9,3 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 889939-79:
(8*8)+(7*8)+(6*9)+(5*9)+(4*3)+(3*9)+(2*7)+(1*9)=281
281 % 10 = 1
So 889939-79-1 is a valid CAS Registry Number.
InChI:InChI=1/C12H16FNO/c13-11-3-1-10(2-4-11)12(9-14)5-7-15-8-6-12/h1-4H,5-9,14H2
889939-79-1Relevant academic research and scientific papers
Synthesis and pharmacological evaluation of 1-alkyl-N-[2-ethyl-2-(4- fluorophenyl)butyl]piperidine-4-carboxamide derivatives as novel antihypertensive agents
Watanuki, Susumu,Matsuura, Keisuke,Tomura, Yuichi,Okada, Minoru,Okazaki, Toshio,Ohta, Mitsuaki,Tsukamoto, Shin-Ichi
, p. 5628 - 5638 (2011/10/12)
We synthesized and evaluated inhibitory activity against T-type Ca 2+ channels for a series of 1-alkyl-N-[2-ethyl-2-(4-fluorophenyl) butyl]piperidine-4-carboxamide derivatives. Structure-activity relationship studies have revealed that dialkyl substituents at the benzylic position play an important role in increasing inhibitory activity. Oral administration of N-[2-ethyl-2-(4-fluorophenyl)butyl]-1-(2-phenylethyl)piperidine-4-carboxamide (20d) lowered blood pressure in spontaneously hypertensive rats without inducing reflex tachycardia, which is often caused by traditional L-type Ca2+ channel blockers.
